SCHEMBL678144

SCHEMBL678144

CC(=O)OC(C)[C@H](N)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.50
TSHR P16473 2/20 0.46
SLC1A3 P43003 4/20 0.43
SLC1A2 P43004 4/20 0.43
SLC1A1 P43005 4/20 0.43
CASR P41180 1/20 0.38
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM1 P11229 1/20 0.35
TBXA2R P21731 1/20 0.35
GALR3 O60755 1/20 0.34
MAPT P10636 1/20 0.34
BLM P54132 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TP53 P04637 1/20 0.33
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678145 1.00 SLC7A5 (0.50) SLC7A5TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL3449733 1.00 SLC7A5 (0.50) SLC7A5TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL22266592 0.86 SLC7A5 (0.46) SLC7A5TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL9980804 0.84 NOS3 (0.44) SLC7A5TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL420691 0.83 TSHR (0.48) SLC7A5TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL28327923 0.83 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2SLC1A1CASR
SCHEMBL684104 0.83 TSHR (0.48) SLC7A5TSHRSLC1A3SLC1A2SLC1A1
Alanine SCHEMBL15322896 0.82 SLC7A5 (0.35) SLC7A5TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL6249367 0.82 SLC7A5 (0.46) SLC7A5TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL17351893 0.81 TSHR (0.46) SLC7A5TSHRCHRM2CHRM4CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113788877-A Novel insect kinin analogs and application thereof in aphid control 中国农业大学 2021-12-14 CN claimed
US-8940791-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2015-01-27 US claimed
US-20140200256-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2014-07-17 US claimed
US-8003683-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2011-08-23 US claimed
US-20070112060-A1 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC 2007-05-17 US claimed
CN-113788877-B Novel insect kinin analogues and application thereof in aphid control 中国农业大学 2023-11-21 CN disclosed
CN-113788877-A Novel insect kinin analogs and application thereof in aphid control 中国农业大学 2021-12-14 CN disclosed
US-8940791-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2015-01-27 US disclosed
EP-2789341-A2 O-acetylated amino acids as anti-platelet agents and nutritional supplements Chandran, V. Ravi (US) 2014-10-15 EP disclosed
US-20140200256-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2014-07-17 US disclosed
US-20110312890-A1 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS SIGNATURE R&D HOLDINGS, LLC (US) 2011-12-22 US disclosed
US-20110275713-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements SIGNATURE R&D HOLDINGS, LLC (US) 2011-11-10 US disclosed
US-8003683-B2 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC (US) 2011-08-23 US disclosed
EP-1957066-A2 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS Chandran, V. Ravi (US) 2008-08-20 EP disclosed
WO-2007059047-A2 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS CHANDRAN V RAVI (US) 2007-05-24 WO disclosed
US-20070112060-A1 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements SIGNATURE R&D HOLDINGS, LLC 2007-05-17 US disclosed
WO-1998053795-A1 COSMETIC AND DERMOPHARMACEUTICAL COMPOSITIONS CONTAINING THREONINE OR SERINE DERIVATIVES SEDERMA S.A. (FR) 1998-12-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140200256-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements PLTP, GP6, PDGFA SLC7A5 500/4885TSHR 3362/4885SLC1A3 591/4885
US-20110312890-A1 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS PLTP, GP6, PDGFA SLC7A5 500/4885TSHR 3362/4885SLC1A3 591/4885
US-20070112060-A1 Acetylated amino acids as anti-platelet agents, nutritional and vitamin supplements PLTP, GP6, PDGFA SLC7A5 500/4885TSHR 3362/4885SLC1A3 591/4885
US-20110275713-A1 Acetylated amino acids as Anti-platelet agents, Nutritional And Vitamin Supplements PLTP, GP6, PDGFA SLC7A5 500/4885TSHR 3362/4885SLC1A3 591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.