Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 7/20 | 0.39 |
| ▸ | ANPEP | P15144 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.35 |
| ▸ | TET3 | O43151 | 1/20 | 0.35 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15772326 | 0.83 | GRIK1 (0.43) | GRIK1GRIK2GRM1GRM2ENPEP | |
| SCHEMBL5201802 | 0.79 | GRIK1 (0.48) | GRIK1GRIK2GRM1GRM2ENPEP | |
| SCHEMBL5275612 | 0.77 | TET2 (0.38) | GRIK1GRIK2GRM1GRM2TET2 | |
| SCHEMBL932746 | 0.77 | — | — | |
| SCHEMBL289109 | 0.77 | — | — | |
| SCHEMBL6515001 | 0.77 | — | — | |
| SCHEMBL9321915 | 0.76 | GRIK1 (0.61) | GRIK1GRIK2GRM1GRM2TET2 | |
| SCHEMBL50117 | 0.76 | GABRP (0.60) | GRIK1GRIK2GRM1GRM2LTA4H | |
| SCHEMBL243507 | 0.76 | TET2 (0.41) | GRIK1GRIK2GRM1GRM2TET2 | |
| Water SCHEMBL10629808 | 0.74 | TET2 (0.40) | GRIK1GRIK2GRM1GRM2TET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1564549-A1 | Calibrating electrochemical sensors, especially pH electrodes | Hamilton Bonaduz AG (CH) | 2005-08-17 | — | — | EP | disclosed |