Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.68 |
| ▸ | HPGD | P15428 | 10/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6249784 | 0.88 | ALDH1A1 (0.60) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL30022879 | 0.81 | ADORA2A (0.55) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL30023092 | 0.81 | ADORA2A (0.55) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL6442951 | 0.74 | KDM4E (0.68) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL30023370 | 0.73 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL30023262 | 0.73 | RXFP1 (0.67) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL28595107 | 0.73 | RXFP1 (0.67) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL28597361 | 0.73 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL7019705 | 0.73 | CYP1A2 (0.61) | ALDH1A1HPGDKDM4EMAPTHSD17B10 | |
| SCHEMBL6440764 | 0.73 | CYP1A2 (1.00) | ALDH1A1HPGDKDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |