Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 19/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625027 | 0.81 | CA12 (0.42) | FYNPIK3CA | |
| SCHEMBL1945371 | 0.79 | FYN (1.00) | FYNPIK3CA | |
| SCHEMBL1945351 | 0.78 | FYN (0.75) | FYN | |
| SCHEMBL1945258 | 0.78 | FYN (1.00) | FYN | |
| SCHEMBL625476 | 0.77 | FYN (0.73) | FYNPIK3CA | |
| SCHEMBL1945181 | 0.77 | FYN (0.87) | FYNPIK3CA | |
| SCHEMBL626624 | 0.77 | PIK3CA (0.56) | FYNPIK3CA | |
| SCHEMBL1944739 | 0.76 | FYN (0.68) | FYN | |
| SCHEMBL1945146 | 0.76 | FYN (1.00) | FYN | |
| SCHEMBL1945193 | 0.76 | FYN (1.00) | FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |