Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 18/20 | 0.73 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1945181 | 0.89 | FYN (0.87) | FYNMKNK1PIK3CA | |
| SCHEMBL624430 | 0.86 | FYN (0.72) | FYNPIK3CA | |
| SCHEMBL625601 | 0.85 | FYN (0.53) | FYNMKNK1 | |
| SCHEMBL625600 | 0.85 | FYN (0.53) | FYNMKNK1 | |
| SCHEMBL624391 | 0.84 | FYN (0.79) | FYNMKNK1 | |
| SCHEMBL1947141 | 0.84 | FYN (1.00) | FYNMKNK1PIK3CA | |
| SCHEMBL30521750 | 0.84 | FYN (1.00) | FYNMKNK1PIK3CA | |
| SCHEMBL625477 | 0.83 | FYN (0.50) | FYNPIK3CA | |
| SCHEMBL624836 | 0.81 | PIM1 (0.59) | FYN | |
| SCHEMBL624132 | 0.78 | MKNK1 (0.48) | FYNMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |