⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL152210 | 0.97 | — | — | |
| Iodide SCHEMBL3822790 | 0.97 | — | — | |
| SCHEMBL16211600 | 0.74 | — | — | |
| SCHEMBL3820394 | 0.74 | NOS3 (0.33) | — | |
| SCHEMBL13140708 | 0.73 | — | — | |
| SCHEMBL21454652 | 0.69 | — | — | |
| SCHEMBL12019020 | 0.67 | SPHK2 (0.36) | — | |
| Hydrochloric Acid SCHEMBL9547112 | 0.67 | — | — | |
| SCHEMBL935269 | 0.67 | — | — | |
| SCHEMBL11955478 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005052563-A1 | PEPTIDE DERIVATIZATION FOR ENHANCING PROTEIN IDENTIFICATION BY MASS SPECTROMETRY | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2005-06-09 | — | — | WO | claimed |
| US-20230132717-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING OR AMELIORATING, OR PREVENTING VIRAL INFECTIONS | UNIV JEFFERSON (US) | 2023-05-04 | — | — | US | disclosed |
| US-20230127965-A1 | METHODS FOR TREATING, AMELIORATING, OR PREVENTING VIRAL INFECTIONS | UNIV JEFFERSON (US) | 2023-04-27 | — | — | US | disclosed |
| US-9550757-B2 | Nuclear transport modulators and uses thereof | Karyopharm Therapeutics Inc. (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160361279-A1 | NOVEL SIGMA RECEPTOR LIGANDS AND METHODS OF MODULATING CELLULAR PROTEIN HOMEOSTASIS USING SAME | Philadelphia Health And Education Corporation, d/b/a Drexel University College of Medicine | 2016-12-15 | — | — | US | disclosed |
| US-9388126-B2 | Sigma receptor ligands and methods of modulating cellular protein homeostasis using same | DREXEL UNIVERSITY (US) | 2016-07-12 | — | — | US | disclosed |
| US-9303000-B2 | Olefin containing nuclear transport modulators and uses thereof | Karyopharm Therapeutics Inc. (US) | 2016-04-05 | — | — | US | disclosed |
| US-20150166472-A1 | NOVEL SIGMA RECEPTOR LIGANDS AND METHODS OF MODULATING CELLULAR PROTEIN HOMEOSTASIS USING SAME | DREXEL UNIVERSITY | 2015-06-18 | — | — | US | disclosed |
| EP-2114869-B1 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2014-07-23 | — | — | EP | disclosed |
| US-20140155370-A1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | Karyopharm Therapeutics Inc. | 2014-06-05 | — | — | US | disclosed |
| US-8513230-B2 | Nuclear transport modulators and uses thereof | KARYOPHARM THERAPEUTICS, INC. (US) | 2013-08-20 | — | — | US | disclosed |
| US-20120258986-A1 | OLEFIN CONTAINING NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | KARYOPHARM THERAPEUTICS, INC. (US) | 2012-10-11 | — | — | US | disclosed |
| US-20110275607-A1 | NUCLEAR TRANSPORT MODULATORS AND USES THEREOF | KARYOPHARM THERAPEUTICS, INC. (US) | 2011-11-10 | — | — | US | disclosed |
| US-20090036450-A1 | PYRAZOLE COMPOUNDS AND USE THEREOF | JAPAN TOBACCO, INC. (JP) | 2009-02-05 | — | — | US | disclosed |
| US-20090036450-A1 | PYRAZOLE COMPOUNDS AND USE THEREOF | JAPAN TOBACCO, INC. (JP) | 2009-02-05 | — | — | US | disclosed |
| CN-1324960-C | Surfactants for use in agricultural formulations | HENKEL CORP (US) | 2007-07-11 | — | — | CN | disclosed |
| WO-2005052563-A1 | PEPTIDE DERIVATIZATION FOR ENHANCING PROTEIN IDENTIFICATION BY MASS SPECTROMETRY | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |
| CN-1267188-A | Surfactants for use in agricultural formulations | HENKEL CORP (US) | 2000-09-20 | — | — | CN | disclosed |