Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96239 | 0.87 | TAAR1 (0.54) | IDO1TAAR1KIF11PSEN1PSEN2 | |
| Hydrochloric Acid SCHEMBL30282379 | 0.85 | IDO1 (0.54) | IDO1TAAR1KIF11PSEN1PSEN2 | |
| Hydroxyamine SCHEMBL9048789 | 0.83 | TAAR1 (0.56) | IDO1TAAR1KIF11PSEN1PSEN2 | |
| SCHEMBL2240656 | 0.83 | HTR2C (0.42) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL2417142 | 0.82 | HAO1 (0.53) | HAO1MLYCDSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10887327 | 0.82 | TSHR (0.48) | SLC6A4ALDH1A1 | |
| SCHEMBL1781036 | 0.81 | KIF11 (0.58) | IDO1TAAR1KIF11PSEN1PSEN2 | |
| SCHEMBL5509990 | 0.81 | SRD5A2 (0.55) | IDO1TAAR1KIF11PSEN1PSEN2 | |
| SCHEMBL15437156 | 0.81 | TAAR1 (0.59) | IDO1TAAR1MAOB | |
| Fluoride SCHEMBL29094698 | 0.80 | HAO1 (0.52) | HAO1MLYCDSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047238-A2 | METHOD FOR SYNTHESISING DIARYL ALCOHOL SULPHIDE COMPOUNDS IN A SOLID PHASE | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-05-26 | — | — | WO | claimed |
| WO-2005047238-A2 | METHOD FOR SYNTHESISING DIARYL ALCOHOL SULPHIDE COMPOUNDS IN A SOLID PHASE | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-05-26 | — | — | WO | disclosed |