Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.72 |
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA9 | Q16790 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.51 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29412397 | 0.98 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL1646800 | 0.98 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL1646304 | 0.98 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL28807082 | 0.98 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL1646303 | 0.98 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL9482158 | 0.98 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL126741 | 0.98 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL9482170 | 0.98 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL20991565 | 0.98 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL14691303 | 0.93 | SNCA (0.69) | SNCAPTGS1ACHECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786247-B1 | SUSTAINED-RELEASE AROMATIC AND METHOD OF DETECTING MICROORGANISM BY USING THE SAME | KANEBO COSMETICS INC (JP) | 2005-08-17 | — | — | EP | disclosed |
| EP-0786247-A1 | SUSTAINED-RELEASE AROMATIC AND METHOD OF DETECTING MICROORGANISM BY USING THE SAME | KANEBO, LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |