Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.75 |
| ▸ | ACHE | P22303 | 1/20 | 0.68 |
| ▸ | CA12 | O43570 | 4/20 | 0.64 |
| ▸ | CA1 | P00915 | 4/20 | 0.64 |
| ▸ | CA9 | Q16790 | 4/20 | 0.64 |
| ▸ | CA2 | P00918 | 2/20 | 0.64 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20991565 | 1.00 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL126741 | 1.00 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL28807082 | 1.00 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL1646800 | 1.00 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL29412397 | 1.00 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL1646303 | 1.00 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL9482158 | 1.00 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL1646304 | 1.00 | SNCA (0.76) | SNCAPTGS1ACHECA12CA1 | |
| Alcohol SCHEMBL6250759 | 0.98 | SNCA (0.72) | SNCAPTGS1ACHECA12CA1 | |
| SCHEMBL14691303 | 0.95 | SNCA (0.69) | SNCAPTGS1ACHECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5221606-A | REAGENT AND KIT FOR ENZYME ASSAY COMPRISING A SUBSTRATE CONSONANT WITH GIVEN ENZYME TO BE ASSAYED | KING'S COLLEGE LONDON (GB) | 1993-06-22 | — | — | US | disclosed |
| EP-0375723-A1 | SUBSTRATES FOR THE ASSAY OF ENZYMES. | KING S COLLEGE LONDON (GB) | 1990-07-04 | — | — | EP | disclosed |
| WO-1989002473-A1 | SUBSTRATES FOR THE ASSAY OF ENZYMES | KING'S COLLEGE LONDON (GB) | 1989-03-23 | — | — | WO | disclosed |
| US-4318986-A | Enzyme assays | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1982-03-09 | — | — | US | disclosed |
| EP-0007372-A1 | Methods and reagents for the assay of enzymes | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1980-02-06 | — | — | EP | disclosed |
| WO-1979000255-A1 | ENZYME ASSAYS | NAT RES DEV (GB) | 1979-05-17 | — | — | WO | disclosed |