Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 3/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257040 | 0.85 | ROCK1 (0.40) | ROCK1PRNPRXFP1GPR3L3MBTL1 | |
| SCHEMBL6254662 | 0.84 | L3MBTL1 (0.46) | GPR3L3MBTL1ITGA4 | |
| SCHEMBL6256271 | 0.83 | ROCK1 (0.36) | ROCK1PRNPRXFP1GPR3L3MBTL1 | |
| SCHEMBL6255467 | 0.81 | ROCK1 (0.38) | ROCK1PRNPRXFP1GPR3L3MBTL1 | |
| SCHEMBL6256272 | 0.81 | L3MBTL1 (0.46) | GPR3L3MBTL1ITGA4 | |
| SCHEMBL6252803 | 0.80 | ROCK1 (0.37) | ROCK1PRNPRXFP1GPR3L3MBTL1 | |
| SCHEMBL6254901 | 0.79 | PLA2G10 (0.34) | GPR3L3MBTL1ALDH1A1ITGA4 | |
| SCHEMBL4262796 | 0.77 | ROCK1 (0.49) | ROCK1PRNPRXFP1GPR3L3MBTL1 | |
| SCHEMBL6256327 | 0.73 | ROCK1 (0.36) | ROCK1L3MBTL1ALDH1A1 | |
| SCHEMBL6254367 | 0.70 | L3MBTL1 (0.47) | GPR3L3MBTL1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143538-B1 | Organic electroluminescent element containing a silacyclopentadiene derivative | CHISSO CORP (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0754691-B1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| EP-0754691-A2 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |