Coumarin

Coumarin

SCHEMBL6252

O=c1ccc2ccccc2o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 11/20 1.00
CA9 Q16790 11/20 1.00
CA1 P00915 7/20 1.00
CA3 P07451 7/20 1.00
CA4 P22748 7/20 1.00
CA7 P43166 7/20 1.00
CA14 Q9ULX7 7/20 1.00
CA5A P35218 6/20 1.00
CA6 P23280 6/20 1.00
CA5B Q9Y2D0 5/20 1.00
CA2 P00918 5/20 1.00
MCL1 Q07820 4/20 1.00
TDP1 Q9NUW8 3/20 1.00
LMNA P02545 3/20 1.00
SOST Q9BQB4 1/20 1.00
PGR P06401 2/20 0.57
ALDH1A1 P00352 5/20 0.54
HPGD P15428 5/20 0.54
HSD17B10 Q99714 4/20 0.54
KDM4E B2RXH2 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumarin SCHEMBL3441294 1.00 CA12 (1.00) CA12CA9CA1CA3CA4
Coumarin SCHEMBL28886137 1.00 CA12 (1.00) CA12CA9CA1CA3CA4
Coumarin SCHEMBL29385611 1.00 CA12 (1.00) CA12CA9CA1CA3CA4
Coumarin SCHEMBL1038138 1.00 CA12 (1.00) CA12CA9CA1CA3CA4
Coumarin SCHEMBL621751 1.00 CA12 (1.00) CA12CA9CA1CA3CA4
Coumarin SCHEMBL8144767 0.98 CA12 (0.95) CA12CA9CA1CA3CA4
Coumarin SCHEMBL382038 0.98 CA12 (0.95) CA12CA9CA1CA3CA4
Coumarin SCHEMBL1193624 0.98 CA12 (0.95) CA12CA9CA1CA3CA4
Coumarin SCHEMBL22721260 0.98 CA12 (0.95) CA12CA9CA1CA3CA4
Coumarin SCHEMBL531571 0.98 CA12 (0.95) CA12CA9CA1CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 230778 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260150492-A1 ORGANIC LIGHT-EMITTING DEVICE AND ELECTRONIC APPARATUS INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2026-05-28 US claimed
US-20260146170-A1 THREE-DIMENSIONALLY PRINTED PARTS AND SECOND-GENERATION PRODUCTS FORMED THEREFROM PERIDOT PRINT LLC (US) 2026-05-28 US claimed
EP-4746708-A1 VOC COMPOSITION AND MINERAL CARRIER THEREOF Agriodor (FR) 2026-05-27 EP claimed
EP-4289275-B1 INSECT REPELLENT COMPOSITION UNIV WIEN BODENKULTUR (AT) 2026-05-27 EP claimed
CN-122079945-A Coumarin derivative containing substituted phenyl ether structure, preparation method and application thereof 2026-05-26 CN claimed
CN-122079862-A Natural product 3-methyl carbazole derivative and preparation method and application thereof 2026-05-26 CN claimed
US-12637679-B2 Aptamer based system to quantify anti-thrombin III in blood UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-05-26 US claimed
CN-122080518-A High-aging-resistance vinyl elastomer material and preparation method thereof 2026-05-26 CN claimed
CN-122080821-A Fluorescent polyolefin adhesive and preparation method and application thereof 2026-05-26 CN claimed
CN-121202849-B Coumarin-pyrazole ring hybridization derivative and preparation method and application thereof NORTHWEST UNIVERSITY (CN) 2026-05-26 CN claimed
US-3955034-A Three-component ceramic coating for silica insulation NASA 1976-05-04 US claimed
US-3953646-A Two-component ceramic coating for silica insulation NASA 1976-04-27 US claimed
US-3949896-A SEAMED ARTICLE LUC PENELOPE JANE VESEY 1976-04-13 US claimed
US-3947412-A CYCLIZATION IN THE PRESENCE OF HEAVY METALS BAYER AKTIENGESELLSCHAFT (DT) 1976-03-30 US claimed
US-3937266-A Method for application of wear-resistant coating FORD MOTOR COMPANY (US) 1976-02-10 US claimed
US-3936473-A COPPER OR NOBLE METAL SALT, OXYGEN AND ORGANIC ACID CATALYST UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-02-03 US claimed
US-3933847-A DYES; REACTING A DIAMINE WITH SULFURIC ACID; ALKYLATION SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-01-20 US claimed
US-3932656-A SYNTHETIC POLYMER, PROSTAGLANDIN ALZA CORPORATION (US) 1976-01-13 US claimed
US-3932200-A ELECTROSLAG JAPAN STEEL WORKS, LTD. (JA) 1976-01-13 US claimed
US-3931026-A ELECTRICALLY INSULATING ENCAPSULATING COMPOSITION FOR SEMICONDUCTOR DEVICES SEMIKRON GESELLSCHAFT FUR GLEICHRICHTERBAU UND ELEKTRONIK M.B.H. (DT) 1976-01-06 US claimed