Coumarin

Coumarin

SCHEMBL621751

O=c1ccc2ccccc2o1.O=c1ccc2ccccc2o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 11/20 1.00
CA9 Q16790 11/20 1.00
CA1 P00915 7/20 1.00
CA3 P07451 7/20 1.00
CA4 P22748 7/20 1.00
CA7 P43166 7/20 1.00
CA14 Q9ULX7 7/20 1.00
CA5A P35218 6/20 1.00
CA6 P23280 6/20 1.00
CA5B Q9Y2D0 5/20 1.00
CA2 P00918 5/20 1.00
MCL1 Q07820 4/20 1.00
TDP1 Q9NUW8 3/20 1.00
LMNA P02545 3/20 1.00
SOST Q9BQB4 1/20 1.00
PGR P06401 2/20 0.57
ALDH1A1 P00352 5/20 0.54
HPGD P15428 5/20 0.54
HSD17B10 Q99714 4/20 0.54
KDM4E B2RXH2 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Coumarin SCHEMBL3441294 1.00 CA12 (1.00) CA12CA9CA1CA3CA4
Coumarin SCHEMBL28886137 1.00 CA12 (1.00) CA12CA9CA1CA3CA4
Coumarin SCHEMBL6252 1.00 CA12 (1.00) CA12CA9CA1CA3CA4
Coumarin SCHEMBL29385611 1.00 CA12 (1.00) CA12CA9CA1CA3CA4
Coumarin SCHEMBL1038138 1.00 CA12 (1.00) CA12CA9CA1CA3CA4
Coumarin SCHEMBL8144767 0.98 CA12 (0.95) CA12CA9CA1CA3CA4
Coumarin SCHEMBL382038 0.98 CA12 (0.95) CA12CA9CA1CA3CA4
Coumarin SCHEMBL1193624 0.98 CA12 (0.95) CA12CA9CA1CA3CA4
Coumarin SCHEMBL22721260 0.98 CA12 (0.95) CA12CA9CA1CA3CA4
Coumarin SCHEMBL531571 0.98 CA12 (0.95) CA12CA9CA1CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924257-A Water-soluble coumarin Fe3+Fluorescent probe, preparation method thereof and application thereof in zebra fish imaging 广西中医药大学 2024-04-26 CN claimed
EP-2486078-B1 A LATENT CURING AGENT AND EPOXY COMPOSITIONS CONTAINING THE SAME HENKEL AG & CO KGAA (DE) 2018-02-21 EP claimed
CN-105368806-B A kind of Fixedpoint mutation modified yeast dipeptidyl peptidase II I 暨南大学 2016-08-24 CN claimed
CN-117924257-A Water-soluble coumarin Fe3+Fluorescent probe, preparation method thereof and application thereof in zebra fish imaging 广西中医药大学 2024-04-26 CN disclosed
CN-116970145-A Amphiphilic triblock polymer, stimulus-responsive nanoparticle and preparation method thereof 中国科学技术大学 2023-10-31 CN disclosed
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
CN-110455964-A The analysis of Coumarins ingredient and identification method in decomposite leaf Radix Angelicae Pubescentis alcohol extract UNIV JIANGXI TRADITIONAL CHINESE MEDICINE 2019-11-15 CN disclosed
EP-3465198-A1 METHOD OF RESOLVING ALLERGENS IN PERFUME INGREDIENTS Givaudan S.A. (CH) 2019-04-10 EP disclosed
US-20180363157-A1 ENVIRONMENTALLY FRIENDLY NICKEL ELECTROPLATING COMPOSITIONS AND METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-12-20 US disclosed
US-20180363156-A1 ENVIRONMENTALLY FRIENDLY NICKEL ELECTROPLATING COMPOSITIONS AND METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2018-12-20 US disclosed
US-20180253534-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-09-06 US disclosed
WO-2002053125-A2 SKIN CARE PRODUCT CONTAINING A RETINOID AND A RETINOID BOOSTER SYSTEM IN A DUAL COMPARTMENT PACKAGE UNILEVER PLC (GB) 2002-07-11 WO disclosed
WO-2002041849-A2 MILD COSMETIC COMPOSITION WITH STABILIZED RETINOIDS UNILEVER PLC (GB) 2002-05-30 WO disclosed
US-6337095-B1 Process for the isolation of compound scopoletin useful as nitric oxide synthesis inhibitor COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-01-08 US disclosed
CN-1216209-A ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE IDEMITSU KOSAN CO (JP) 1999-05-05 CN disclosed
US-5710406-A Deodorizing cigarette lighter GARRIS LOUIE G (US) 1998-01-20 US disclosed
US-5686243-A DETECTING POLYNUCLEOTIDE SEQUENCES; HYBRIDIZATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-11-11 US disclosed
US-4832812-A REUSE OF ELECTROLYTE ECO-TEC LIMITED (CA) 1989-05-23 US disclosed
US-4778572-A RECOVERING METAL SALT SOLUTION AND RECYCLING TO MAINTAIN CONCENTRATION; ANODE EQUAL TO CATHODE EFFICIENCY ECO-TEC LIMITED (CA) 1988-10-18 US disclosed
US-4299450-A Elastomer display SHARP KABUSHIKI KAISHA (JP) 1981-11-10 US disclosed