Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28327160 | 0.75 | TDP1 (0.42) | ALDH1A1TDP1RECQLMEN1MAPT | |
| SCHEMBL10778388 | 0.75 | ALDH1A1 (0.37) | ALDH1A1TDP1RECQLMEN1MAPT | |
| SCHEMBL134429 | 0.73 | ALDH1A1 (0.40) | ALDH1A1TDP1RECQLMEN1MAPT | |
| SCHEMBL865959 | 0.73 | ALDH1A1 (0.42) | ALDH1A1TDP1RECQLMEN1MAPT | |
| SCHEMBL28198484 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TDP1RECQLMEN1MAPT | |
| SCHEMBL1287162 | 0.71 | ERBB2 (0.39) | ALDH1A1TDP1RECQLMEN1MAPT | |
| SCHEMBL2257187 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TDP1RECQLMEN1MAPT | |
| SCHEMBL26444866 | 0.70 | ALDH1A1 (0.37) | ALDH1A1TDP1RECQLMEN1MAPT | |
| Water SCHEMBL28540739 | 0.70 | ERBB2 (0.38) | ALDH1A1TDP1RECQLMEN1MAPT | |
| SCHEMBL8049734 | 0.68 | ALDH1A1 (0.36) | ALDH1A1TDP1RECQLMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1566169-A1 | Cosmetic compositions containing combinations of Bupleurum species extracts and Salvia miltiorrhiza extracts for the treatment and reduction of blemishes caused by cellulite | ABOCA S.p.A. (IT) | 2005-08-24 | — | — | EP | disclosed |