SCHEMBL6252387

SCHEMBL6252387

C1=C\CCC(C2CC/C=C\CCC2)CCC/1

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
ALOX15 P16050 1/20 0.31
PSMB1 P20618 1/20 0.30
PSMB8 P28062 1/20 0.30
PSMB9 P28065 1/20 0.30
PSMB5 P28074 1/20 0.30
PSMB10 P40306 1/20 0.30
PSMB2 P49721 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6252389 1.00 ALDH1A1 (0.44) ALDH1A1ALOX15PSMB1PSMB8PSMB9
SCHEMBL25399677 0.97 ALDH1A1 (0.41) ALDH1A1
SCHEMBL2831619 0.97 ALDH1A1 (0.41) ALDH1A1
SCHEMBL2831616 0.97 ALDH1A1 (0.41) ALDH1A1
SCHEMBL19018800 0.90 ALDH1A1 (0.47) ALDH1A1ALOX15
SCHEMBL7059071 0.87 ALDH1A1 (0.53) ALDH1A1
SCHEMBL7059073 0.87 ALDH1A1 (0.53) ALDH1A1
SCHEMBL3488420 0.84 ALDH1A1 (0.50) ALDH1A1
SCHEMBL3488418 0.84 ALDH1A1 (0.50) ALDH1A1
Potassium SCHEMBL7061708 0.84 ALDH1A1 (0.50) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005055953-A2 METHODS OF PREVENTING AND TREATING GASTROINTESTINAL DYSFUNCTION ADOLOR CORPORATION (US) 2005-06-23 WO disclosed
US-4167947-A Substituted bicyclooctenemethanols, process for producing same and uses of same for augmenting or enhancing the organoleptic properties of smoking compositions INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-09-18 US disclosed
US-4166916-A ENHANCES ORGANOLEPTIC PROPERTIES OF TOBACCOS AND PERFUMES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-09-04 US disclosed
US-4163737-A Substituted bicyclooctenemethanols, process for producing same and uses of same for augmenting or enhancing the organoleptic properties of tobaccos, perfumes and perfumed articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-08-07 US disclosed
US-4139484-A SOAPS, PERFUMES INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-02-13 US disclosed
US-4128729-A ORGANOLEPTIC INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1978-12-05 US disclosed
US-3967629-A Bicyclic fragrance materials and processes therefor INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-07-06 US disclosed