Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.51 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.45 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.45 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.45 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365810 | 0.83 | AOC3 (0.48) | AOC3 | |
| SCHEMBL10031025 | 0.77 | MEN1 (0.71) | EPHX2FAAHTRPV1AOC3PADI1 | |
| SCHEMBL5362814 | 0.76 | KCNB1 (0.42) | — | |
| SCHEMBL5355946 | 0.76 | KDM4C (0.42) | — | |
| SCHEMBL5360875 | 0.76 | PTPN11 (0.44) | AOC3 | |
| SCHEMBL5360954 | 0.75 | ALOX15 (0.42) | EPHX2 | |
| SCHEMBL5365598 | 0.75 | PTPN11 (0.41) | AOC3LTB4R2 | |
| SCHEMBL4970472 | 0.74 | EPHX2 (0.61) | EPHX2FAAHTRPV1CNR1CNR2 | |
| SCHEMBL10031029 | 0.74 | MEN1 (0.71) | EPHX2FAAHTRPV1AOC3PADI1 | |
| SCHEMBL2762512 | 0.74 | EPHX2 (0.79) | EPHX2FAAHTRPV1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572629-A1 | COMPOUNDS WHICH MODULATE PPARϝ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004052840-A1 | COMPOUNDS WHICH MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-24 | — | — | WO | disclosed |