Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 19/20 | 0.64 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625325 | 0.82 | FYN (0.55) | FYN | |
| SCHEMBL624007 | 0.81 | PIM1 (0.51) | FYNPIM1PIM2 | |
| SCHEMBL623808 | 0.81 | FYN (0.55) | FYNPIM1PIM2 | |
| SCHEMBL12545618 | 0.78 | FYN (1.00) | FYNPIM1PIM2 | |
| SCHEMBL1946229 | 0.78 | FYN (0.85) | FYNPIM1PIM2 | |
| SCHEMBL2250764 | 0.78 | FYN (0.81) | FYNPIM1PIM2 | |
| SCHEMBL1946859 | 0.77 | FYN (1.00) | FYN | |
| SCHEMBL627316 | 0.76 | FYN (0.34) | FYN | |
| SCHEMBL625674 | 0.75 | PIK3CA (0.50) | FYN | |
| SCHEMBL2252495 | 0.74 | FYN (0.69) | FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |