Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 15/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.30 |
| ▸ | PI4KA | P42356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625325 | 0.80 | FYN (0.55) | FYNMKNK1HASPIN | |
| SCHEMBL625258 | 0.76 | FYN (0.64) | FYN | |
| SCHEMBL625674 | 0.74 | PIK3CA (0.50) | FYN | |
| SCHEMBL624007 | 0.74 | PIM1 (0.51) | FYNHASPIN | |
| SCHEMBL626888 | 0.69 | AAK1 (0.34) | — | |
| SCHEMBL623857 | 0.68 | PIM1 (0.33) | MKNK1 | |
| SCHEMBL626175 | 0.65 | FYN (0.46) | FYNMKNK1HASPIN | |
| SCHEMBL1650182 | 0.65 | ALPL (0.46) | FYNMKNK1HASPIN | |
| SCHEMBL627167 | 0.64 | FYN (0.46) | FYNHASPIN | |
| SCHEMBL628254 | 0.63 | MKNK1 (0.57) | FYNMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020215-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |