Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.65 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.65 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.65 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.65 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.64 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.64 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | GSK3A | P49840 | 2/20 | 0.61 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.61 |
| ▸ | HINT1 | P49773 | 4/20 | 0.58 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | PNP | P00491 | 2/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanosine SCHEMBL27427138 | 0.93 | P2RY2 (0.57) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| Guanosine SCHEMBL8024690 | 0.93 | P2RY2 (0.57) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| Guanosine SCHEMBL8024691 | 0.91 | P2RY2 (0.56) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| SCHEMBL22612692 | 0.91 | P2RY2 (0.63) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY2 | |
| E626 SCHEMBL8659516 | 0.91 | P2RY2 (0.72) | P2RY2P2RY4P2RY6GSK3ARPS6KA3 | |
| Guanosine SCHEMBL24049417 | 0.90 | HPGD (0.76) | HPGDGSK3ARPS6KA3MAPK14HINT1 | |
| Guanosine SCHEMBL24049467 | 0.90 | HPGD (0.76) | HPGDGSK3ARPS6KA3MAPK14HINT1 | |
| Guanosine SCHEMBL11986902 | 0.90 | HPGD (0.76) | HPGDGSK3ARPS6KA3MAPK14HINT1 | |
| Guanosine SCHEMBL24049416 | 0.90 | HPGD (0.76) | HPGDGSK3ARPS6KA3MAPK14HINT1 | |
| Guanosine SCHEMBL20750695 | 0.90 | HPGD (0.76) | HPGDGSK3ARPS6KA3MAPK14HINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118256490-A | Cyclic RNA, compositions and methods of treating diseases | 麻省理工学院 | 2024-06-28 | — | — | CN | disclosed |
| US-20240158807-A1 | Circular RNA For Translation In Eukaryotic Cells | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2024-05-16 | — | — | US | disclosed |
| US-11981909-B2 | Circular RNA for translation in eukaryotic cells | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2024-05-14 | — | — | US | disclosed |
| US-11845950-B2 | Circular RNA for translation in eukaryotic cells | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-12-19 | — | — | US | disclosed |
| EP-3578659-B1 | ARTIFICIAL NUCLEIC ACID MOLECULES FOR IMPROVED PROTEIN OR PEPTIDE EXPRESSION | CureVac SE (DE) | 2023-11-01 | — | — | EP | disclosed |
| WO-2023135505-A1 | TLR7/8-ANTAGONIST FOR TREATING SJÖGREN'S SYNDROME OR MIXED CONNECTIVE TISSUE DISEASE | NOVARTIS AG (CH) | 2023-07-20 | — | — | WO | disclosed |
| CN-116056719-A | Pharmaceutical composition comprising a combination of guanylate cyclase C (GUCY 2C) agonist and a short chain fatty acid or prodrug thereof | 索伦·欧克维克 | 2023-05-02 | — | — | CN | disclosed |
| US-20230050306-A1 | Circular RNA For Translation In Eukaryotic Cells | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2023-02-16 | — | — | US | disclosed |
| CN-108570468-B | Nucleic acids comprising or encoding a histone stem-loop and a polyadenylation sequence or polyadenylation signal to increase expression of a gene encoding a therapeutic protein | 库瑞瓦格股份公司 | 2022-11-25 | — | — | CN | disclosed |
| US-11352641-B2 | Circular RNA for translation in eukaryotic cells | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-06-07 | — | — | US | disclosed |
| EP-0389564-B1 | DETECTION OF SALMONELLA | AMOCO CORP (US) | 1996-01-24 | — | — | EP | disclosed |
| EP-0641384-A1 | VIRUS RESISTANT PLANTS CONTAINING INDUCIBLE CYTOTOXIC mRNAs | RIBOZYME PHARMACEUTICALS, INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0635023-A1 | COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993023532-A1 | VIRUS RESISTANT PLANTS CONTAINING INDUCIBLE CYTOTOXIC mRNAs | RIBOZYME PHARMACEUTICALS, INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| EP-0568641-A1 | REGULATION OF NUCLEIC ACID TRANSLATION | UNITED STATES BIOCHEMICAL CORPORATION (US) | 1993-11-10 | — | — | EP | disclosed |
| WO-1993018052-A1 | COVALENTLY CROSS-LINKED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1993-09-16 | — | — | WO | disclosed |
| EP-0389564-A4 | DETECTION OF SALMONELLA | — | 1993-03-17 | — | — | EP | disclosed |
| WO-1992013070-A1 | REGULATION OF NUCLEIC ACID TRANSLATION | UNITED STATES BIOCHEMICAL CORPORATION (US) | 1992-08-06 | — | — | WO | disclosed |
| EP-0389564-A1 | DETECTION OF SALMONELLA. | INTEGRATED GENETICS INC (US) | 1990-10-03 | — | — | EP | disclosed |
| WO-1989005359-A1 | DETECTION OF SALMONELLA | INTEGRATED GENETICS, INC. (US) | 1989-06-15 | — | — | WO | disclosed |