Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 1/20 | 0.56 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.56 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.56 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.54 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.54 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GSK3A | P49840 | 2/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
| ▸ | HINT1 | P49773 | 5/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | PNP | P00491 | 2/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanosine SCHEMBL439084 | 0.95 | P2RY2 (0.52) | P2RY2P2RY4P2RY6SLC28A1SLC28A2 | |
| Uridine SCHEMBL3345043 | 0.92 | SLC28A1 (0.64) | P2RY2P2RY4P2RY6SLC28A1SLC28A2 | |
| Guanosine SCHEMBL8995759 | 0.92 | HPGD (0.62) | HPGDGSK3ARPS6KA3MAPK14HINT1 | |
| Guanosine SCHEMBL625261 | 0.91 | SLC28A1 (0.65) | P2RY2P2RY4P2RY6SLC28A1SLC28A2 | |
| Guanosine SCHEMBL29045171 | 0.90 | HPGD (0.60) | HPGDGSK3ARPS6KA3MAPK14HINT1 | |
| Guanosine SCHEMBL8024690 | 0.89 | P2RY2 (0.57) | P2RY2P2RY4P2RY6SLC28A1SLC28A2 | |
| Guanosine SCHEMBL3055871 | 0.88 | HPGD (0.63) | HPGDGSK3ARPS6KA3MAPK14HINT1 | |
| Guanosine SCHEMBL27658690 | 0.86 | RNASEL (0.51) | P2RY2P2RY4P2RY6SLC28A1SLC28A2 | |
| Uridine SCHEMBL2226523 | 0.86 | SLC28A1 (0.56) | P2RY2P2RY4P2RY6SLC28A1SLC28A2 | |
| Guanosine SCHEMBL27427138 | 0.84 | P2RY2 (0.57) | P2RY2P2RY4P2RY6SLC28A1SLC28A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017736-A | HIGH YIELD PROCESS BY BASE EXCHANGE REACTION BETWEEN PYRIMIDINE NUCLEOSIDE AND PURINE BASE IN PHOSPHATE ION-CONTAINING AQUEOUS SOLUTION IN PRESENCE OF PURINE AND PYRIMIDINE NUCLEOSIDE PHOSPHORYLASES | YUKI GOSEI KOGYO CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |