Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11159529 | 1.00 | CA2 (0.52) | CA2FFAR4FFAR1LMNADNM1 | |
| SCHEMBL15018263 | 1.00 | CA2 (0.52) | CA2FFAR4FFAR1LMNADNM1 | |
| SCHEMBL7666492 | 0.98 | CA2 (0.48) | CA2FFAR4FFAR1LMNACES2 | |
| SCHEMBL7767174 | 0.98 | CA2 (0.48) | CA2FFAR4FFAR1LMNACES2 | |
| SCHEMBL657401 | 0.98 | CA2 (0.48) | CA2FFAR4FFAR1LMNACES2 | |
| SCHEMBL23498813 | 0.98 | CA2 (0.48) | CA2FFAR4FFAR1LMNACES2 | |
| SCHEMBL16702733 | 0.98 | CA2 (0.48) | CA2FFAR4FFAR1LMNACES2 | |
| SCHEMBL3307047 | 0.98 | CA2 (0.48) | CA2FFAR4FFAR1LMNACES2 | |
| SCHEMBL16209868 | 0.98 | CA2 (0.48) | CA2FFAR4FFAR1LMNACES2 | |
| SCHEMBL10519624 | 0.98 | CA2 (0.48) | CA2FFAR4FFAR1LMNACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572189-A1 | METHOD OF LOWERING CRP AND REDUCING SYSTEMIC INFLAMMATION | Warner-Lambert Company LLC (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004045596-A1 | METHOD OF LOWERING CRP AND REDUCING SYSTEMIC INFLAMMATION | WARNER-LAMBERT COMPANY LLC (US) | 2004-06-03 | — | — | WO | disclosed |
| CN-1100747-C | Terminal carboxy or tetrazole groups containing dialkyl ethers | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | CN | disclosed |
| US-5783600-A | FOR ELEVATING HDL CHOLESTEROL; ANTIDIABETIC AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-07-21 | — | — | US | disclosed |
| US-5756544-A | ADMINISTERING TO LOWER LEVELS OF LOW DENSITY LIPOPROTEINS AND TO RAISE THE LEVELS OF HIGH DENSITY LIPOPROTEINS | WARNER-LAMBERT COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| US-5750569-A | LOWERING PLASMA LIPIDS | WARNER-LAMBERT COMPANY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5648387-A | Carboxyalkylethers, formulations, and treatment of vascular diseases | WARNER-LAMBERT COMPANY (US) | 1997-07-15 | — | — | US | disclosed |