Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997256 | 0.78 | CYP1A2 (0.40) | CYP1A2CYP2C9TSHRHIF1AAR | |
| SCHEMBL30755 | 0.71 | LMNA (0.53) | CYP1A2TSHRARLMNAALDH1A1 | |
| 1,2-Dichloroethane SCHEMBL28234602 | 0.69 | LMNA (0.44) | CYP1A2TSHRARLMNAALDH1A1 | |
| Glycerin SCHEMBL28165911 | 0.69 | LMNA (0.60) | CYP1A2TSHRARLMNAALDH1A1 | |
| SCHEMBL29061893 | 0.69 | LMNA (0.50) | CYP1A2TSHRARLMNAALDH1A1 | |
| SCHEMBL27261364 | 0.69 | LMNA (0.50) | CYP1A2TSHRARLMNAALDH1A1 | |
| Water SCHEMBL28545207 | 0.69 | LMNA (0.50) | CYP1A2TSHRARLMNAALDH1A1 | |
| Water SCHEMBL27953222 | 0.69 | LMNA (0.50) | CYP1A2TSHRARLMNAALDH1A1 | |
| Water SCHEMBL22418486 | 0.69 | LMNA (0.50) | CYP1A2TSHRARLMNAALDH1A1 | |
| SCHEMBL1661544 | 0.68 | CYP1A2 (0.44) | CYP1A2TSHRARLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1215222-B1 | Intumescing two component polyurethane coatings | INTUMEX GMBH (AT) | 2005-09-14 | — | — | EP | disclosed |
| EP-1215222-A1 | Intumescing two component polyurethane coatings | Intumex Brandschutzprodukte AG (AT) | 2002-06-19 | — | — | EP | disclosed |