Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.65 |
| ▸ | ABL1 | P00519 | 5/20 | 0.48 |
| ▸ | BCR | P11274 | 5/20 | 0.48 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797628 | 0.88 | TRPV1 (0.70) | TRPV1ABL1BCRTNNI3K | |
| SCHEMBL5798371 | 0.87 | TRPV1 (0.59) | TRPV1ABL1BCR | |
| SCHEMBL4832759 | 0.86 | TRPV1 (0.87) | TRPV1ABL1BCRTNNI3K | |
| SCHEMBL6033076 | 0.84 | TRPV1 (0.67) | TRPV1ABL1BCRTNNI3K | |
| SCHEMBL13868105 | 0.80 | TRPV1 (1.00) | TRPV1ABL1BCR | |
| SCHEMBL6033561 | 0.78 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL4837497 | 0.78 | TRPV1 (0.76) | TRPV1ABL1BCRTNNI3K | |
| SCHEMBL6252585 | 0.76 | TRPV1 (0.54) | TRPV1ABL1BCRTNNI3K | |
| SCHEMBL5801083 | 0.75 | TRPV1 (0.69) | TRPV1ABL1BCR | |
| SCHEMBL4832960 | 0.74 | ABL1 (0.72) | TRPV1ABL1BCRTNNI3K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047280-A1 | SUBSTITUTED NITROGEN-CONTAINING SIX-MEMBERED AMINO-HETEROCYCLES AS VANILLOID-1 RECEPTOR ANTAGONISTS FOR TREATING PAIN | MERCK SHARP & DOHME LIMITED (GB) | 2005-05-26 | — | — | WO | claimed |