Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | CA5A | P35218 | 2/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.32 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL10747059 | 1.00 | TSHR (0.73) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL16052367 | 1.00 | TSHR (0.73) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL7565260 | 1.00 | TSHR (0.73) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL2315756 | 1.00 | TSHR (0.73) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL8605942 | 1.00 | TSHR (0.73) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL5410924 | 1.00 | TSHR (0.73) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL11908872 | 1.00 | TSHR (0.73) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL10378771 | 1.00 | TSHR (0.73) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL2779397 | 1.00 | TSHR (0.73) | TSHRMEN1ALDH1A1KMT2ACA5A | |
| Sulfuric Acid SCHEMBL9304648 | 1.00 | TSHR (0.73) | TSHRMEN1ALDH1A1KMT2ACA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2603786-A1 | ISOTONIC BUFFERED COMPOSITION AND METHOD THAT ENABLES COUNTING OF CELLS | Beckman Coulter, Inc. (US) | 2013-06-19 | — | — | EP | disclosed |
| WO-2012021458-A1 | ISOTONIC BUFFERED COMPOSITION AND METHOD THAT ENABLES COUNTING OF CELLS | BECKMAN COULTER, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| CN-101503596-B | Preparation of radiation curable halogen-free phosphor- and nitrogen-containing transparent fire-resisting paint | USTC UNIV SCIENCE TECH CN | 2011-06-29 | — | — | CN | disclosed |
| CN-101503581-B | Radiation curable expansion type flame-retardant transparent nano composite coating and preparation thereof | USTC UNIV SCIENCE TECH CN | 2011-06-29 | — | — | CN | disclosed |
| CN-101497756-B | Radiation curable expansion type transparent flame-retardant coating and preparation thereof | USTC UNIV SCIENCE TECH CN | 2011-06-29 | — | — | CN | disclosed |
| CN-101503581-A | Radiation curable expansion type flame-retardant transparent nano composite coating and preparation thereof | USTC UNIV SCIENCE TECH CN (CN) | 2009-08-12 | — | — | CN | disclosed |
| CN-101503596-A | Preparation of radiation curable halogen-free phosphor- and nitrogen-containing transparent fire-resisting paint | USTC UNIV SCIENCE TECH CN (CN) | 2009-08-12 | — | — | CN | disclosed |
| CN-101497756-A | Radiation curable expansion type transparent flame-retardant coating and preparation thereof | USTC UNIV SCIENCE TECH CN (CN) | 2009-08-05 | — | — | CN | disclosed |