Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 5/20 | 0.41 |
| ▸ | SLC2A2 | P11168 | 5/20 | 0.41 |
| ▸ | SLC2A3 | P11169 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839210 | 0.85 | GCK (0.47) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL12000946 | 0.82 | SLC2A1 (0.53) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL839657 | 0.82 | SLC2A1 (0.54) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL849766 | 0.82 | MAPT (0.46) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25343909 | 0.81 | CYP17A1 (0.42) | MAPTKDM4ECYP1A2SLC2A1SLC2A2 | |
| SCHEMBL30568436 | 0.81 | CYP17A1 (0.42) | MAPTKDM4ECYP1A2SLC2A1SLC2A2 | |
| SCHEMBL838945 | 0.80 | MAPK14 (0.41) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL25975269 | 0.80 | MAPT (0.53) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL838829 | 0.79 | P2RX7 (0.46) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL839578 | 0.79 | SLC2A1 (0.56) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047288-A1 | PYRAZOLOPYRIMIDINES AS ANTI - HEPATITS C AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2005-05-26 | — | — | WO | claimed |
| WO-2005047288-A1 | PYRAZOLOPYRIMIDINES AS ANTI - HEPATITS C AGENTS | ARROW THERAPEUTICS LIMITED (GB) | 2005-05-26 | — | — | WO | disclosed |