SCHEMBL6253665

SCHEMBL6253665

CC(C)(C)[Si]1(c2ccccc2)C(c2cccc(C[Si](C)(C)C)n2)=C(c2ccccc2)C(c2ccccc2)=C1c1cccc(C[Si](C)(C)C)n1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SHMT1 P34896 1/20 0.33
TRPV3 Q8NET8 2/20 0.31
MEN1 O00255 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6259223 0.84 TRPV3 (0.33) SHMT1TRPV3MEN1RAB9AKMT2A
SCHEMBL6253624 0.83 MEN1 (0.48) TRPV3MEN1RAB9AKMT2A
SCHEMBL6257961 0.81 MEN1 (0.35) SHMT1TRPV3MEN1RAB9AKMT2A
SCHEMBL6254373 0.81 MEN1 (0.33) MEN1RAB9AKMT2A
SCHEMBL6254050 0.80 CCR1 (0.42) MEN1RAB9AKMT2A
SCHEMBL6256692 0.79 MEN1 (0.33) MEN1RAB9AKMT2A
SCHEMBL7119607 0.79 TRPV3 (0.33) TRPV3MEN1RAB9AKMT2A
SCHEMBL6256330 0.78 TRPV3 (0.33) TRPV3MEN1RAB9AKMT2A
SCHEMBL6257555 0.78
SCHEMBL8163083 0.75 CYP1A1 (0.40) MEN1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1143538-B1 Organic electroluminescent element containing a silacyclopentadiene derivative CHISSO CORP (JP) 2005-09-14 EP disclosed
EP-0754691-B1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORP (JP) 2003-11-19 EP disclosed
EP-1143538-A1 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative Chisso Corporation (JP) 2001-10-10 EP disclosed
US-6051319-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 2000-04-18 US disclosed
US-5986121-A Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1999-11-16 US disclosed
EP-0754691-A2 Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative CHISSO CORPORATION (JP) 1997-01-22 EP disclosed