Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.46 |
| ▸ | P4HB | P07237 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 4/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11873507 | 0.86 | PDE4A (0.36) | DPP4P4HBPDE4APDE4BPDE4C | |
| SCHEMBL11871724 | 0.83 | DPP4 (0.41) | DPP4P4HBPDE4APDE4BPDE4C | |
| SCHEMBL11402658 | 0.82 | DPP4 (0.40) | DPP4P4HBPDE4APDE4BPDE4C | |
| SCHEMBL11850676 | 0.82 | DPP4 (0.40) | DPP4P4HBPDE4APDE4BPDE4C | |
| SCHEMBL30358376 | 0.81 | DPP4 (0.46) | DPP4P4HBPDE4APDE4BPDE4C | |
| SCHEMBL17784927 | 0.81 | DPP4 (0.46) | DPP4P4HBPDE4APDE4BPDE4C | |
| SCHEMBL11251748 | 0.80 | P4HB (0.39) | DPP4P4HBPDE4APDE4BPDE4C | |
| SCHEMBL11876758 | 0.80 | PTPN1 (0.44) | DPP4P4HBPDE4APDE4BPDE4C | |
| SCHEMBL11251503 | 0.80 | DPP4 (0.38) | DPP4P4HBPDE4APDE4BPDE4C | |
| SCHEMBL11251754 | 0.80 | DPP4 (0.38) | DPP4P4HBPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304794-A | 2,4,6,3'-TETRAHYDROXY-4'-METHOXYDIHYDROCALCONE, WATER SOLUBILITY | CHIMICASA GMBH (CH) | 1981-12-08 | — | — | US | claimed |
| US-20200157480-A1 | TASTE MODIFIERS COMPRISING A CHLOROGENIC ACID | GIVAUDAN SA (CH) | 2020-05-21 | — | — | US | disclosed |
| US-10597620-B2 | Taste modifiers comprising a chlorogenic acid | GIVAUDAN SA (CH) | 2020-03-24 | — | — | US | disclosed |
| US-20170327776-A1 | TASTE MODIFIERS COMPRISING A CHLOROGENIC ACID | GIVAUDAN S.A. (CH) | 2017-11-16 | — | — | US | disclosed |
| US-20120189750-A1 | Taste Modifiers Comprising a Chlorogenic Acid | GIVAUDAN SA (CH) | 2012-07-26 | — | — | US | disclosed |
| US-8197875-B2 | to modify or mask the off-taste of artificial sweeteners, soy, alcohol etc.; food products, beverages and pharmaceuticals, contain substances that may provide or cause bitter notes | GIVAUDAN SA (CH) | 2012-06-12 | — | — | US | disclosed |
| EP-1399034-B1 | TASTE MODIFIERS COMPRISING A CHLOROGENIC ACID | GIVAUDAN SA (CH) | 2005-09-28 | — | — | EP | disclosed |
| US-20040213881-A1 | Taste modifiers comprising a chlorogenic acid | CHIEN MINJIEN (US) | 2004-10-28 | — | — | US | disclosed |
| US-20030003212-A1 | Taste modifiers | GIVAUDAN SA (CH) | 2003-01-02 | — | — | US | disclosed |
| US-5336513-A | Adding caffeic acid and ferulic acid to foods containing artificial sweeteners | KRAFT GENERAL FOODS, INC. (US) | 1994-08-09 | — | — | US | disclosed |
| US-4304794-A | 2,4,6,3'-TETRAHYDROXY-4'-METHOXYDIHYDROCALCONE, WATER SOLUBILITY | CHIMICASA GMBH (CH) | 1981-12-08 | — | — | US | disclosed |
| US-4304794-A | 2,4,6,3'-TETRAHYDROXY-4'-METHOXYDIHYDROCALCONE, WATER SOLUBILITY | CHIMICASA GMBH (CH) | 1981-12-08 | — | — | US | disclosed |
| US-4254155-A | Preparing neohesperidin dihydrochalcone sweetener composition | CHIMICASA GMBH (CH) | 1981-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157480-A1 | TASTE MODIFIERS COMPRISING A CHLOROGENIC ACID | TAS2R60, TAS2R43, TAS2R7 | DPP4 1109/4885P4HB 4523/4885PDE4A 2840/4885 |
| US-10597620-B2 | Taste modifiers comprising a chlorogenic acid | TAS2R60, TAS2R43, TAS2R7 | DPP4 1109/4885P4HB 4523/4885PDE4A 2840/4885 |
| US-20170327776-A1 | TASTE MODIFIERS COMPRISING A CHLOROGENIC ACID | TAS2R60, TAS2R43, TAS2R7 | DPP4 1109/4885P4HB 4523/4885PDE4A 2840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.