Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254119 | 1.00 | ADRB2 (0.41) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL6257023 | 0.94 | ADRB2 (0.38) | ADRB2ADRB1BRD4ADRB3 | |
| SCHEMBL694574 | 0.94 | ADRB2 (0.38) | ADRB2ADRB1BRD4ADRB3 | |
| SCHEMBL6257028 | 0.94 | ADRB2 (0.38) | ADRB2ADRB1BRD4ADRB3 | |
| SCHEMBL729897 | 0.94 | ADRB2 (0.38) | ADRB2ADRB1BRD4ADRB3 | |
| SCHEMBL729898 | 0.94 | ADRB2 (0.38) | ADRB2ADRB1BRD4ADRB3 | |
| SCHEMBL730381 | 0.88 | ADRB2 (0.38) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL704784 | 0.88 | ADRB2 (0.38) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL730380 | 0.88 | ADRB2 (0.38) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL2142809 | 0.88 | ADRB3 (0.39) | ADRB2ADRB1DRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1574501-A1 | Quinolinone derivatives, pharmaceutical compositions containing them and their use | Pfizer Limited (GB) | 2005-09-14 | — | — | EP | disclosed |