SCHEMBL6254130

SCHEMBL6254130

C=CC[N]C1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.39
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11082364 0.74 TSHR (0.36) GAATSHRMAPK1
SCHEMBL5098304 0.69 RECQL (0.33) GAATSHRMAPK1
SCHEMBL3964647 0.69 GAA (0.42) GAATSHR
SCHEMBL3916791 0.68 GAA (0.42) GAA
SCHEMBL9147137 0.68 TSHR (0.33) TSHR
SCHEMBL1680402 0.68
SCHEMBL9372911 0.68 RECQL (0.35) TSHRMAPK1
SCHEMBL10780847 0.67 MAPK1 (0.41) GAATSHRMAPK1
SCHEMBL10715023 0.64 ATM (0.31) MAPK1
SCHEMBL1680251 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0819730-B1 Ozone resistant long-time stabilisers CIBA SC HOLDING AG (CH) 2005-04-06 EP disclosed
US-5965641-A A STERICALLY HINDERED PIPERIDINE COMPOUND, OR AN OLIGOMERIC OR POLYMERIC STERICALLY HINDERED PIPERIDINE COMPOUND CONTAINING ONE OR SEVERAL TRIAZINE UNITS; RADIATION RESISTANCE, OXIDATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-10-12 US disclosed
EP-0819730-A2 Ozone resistant long-time stabilisers Ciba SC Holding AG (CH) 1998-01-21 EP disclosed