Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372911 | 0.78 | RECQL (0.35) | RECQLMAPK1TSHRALDH1A1POLB | |
| SCHEMBL12955381 | 0.75 | — | — | |
| SCHEMBL8482728 | 0.74 | MAPK1 (0.36) | RECQLMAPK1TSHRALDH1A1POLB | |
| SCHEMBL2254659 | 0.73 | ALDH1A1 (0.49) | RECQLMAPK1TSHRALDH1A1POLB | |
| SCHEMBL24044018 | 0.72 | — | — | |
| SCHEMBL10780847 | 0.72 | MAPK1 (0.41) | RECQLMAPK1TSHRALDH1A1POLB | |
| SCHEMBL11082364 | 0.70 | TSHR (0.36) | RECQLMAPK1TSHRGAA | |
| SCHEMBL6254130 | 0.69 | GAA (0.39) | MAPK1TSHRGAA | |
| SCHEMBL1579416 | 0.69 | RECQL (0.37) | RECQLMAPK1ALDH1A1GAA | |
| SCHEMBL4758990 | 0.67 | RECQL (0.39) | RECQLMAPK1TSHRALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105917737-A | Composite gas barrier laminate and method for producing same | 日本瑞翁株式会社 | 2016-08-31 | — | — | CN | disclosed |
| CN-104137277-B | Solar cell sealing chip module | 三井化学东赛璐株式会社 | 2016-08-24 | — | — | CN | disclosed |
| US-7442713-B2 | 2-thio-substituted imidazole derivatives and their use in pharmaceutics | MERCKLE GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-7253191-B2 | 2-thio-substituted imidazole derivatives and the use thereof in the pharmaceutical industry | MERCKLE GMBH (DE) | 2007-08-07 | — | — | US | disclosed |
| US-20060252810-A1 | 2-Thio-substituted imidazole derivatives and their use in pharmaceutics | LAUFER STEFAN | 2006-11-09 | — | — | US | disclosed |
| EP-1506187-A1 | 2-THIO-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR USE IN PHARMACEUTICS | MERCKLE GMBH (DE) | 2005-02-16 | — | — | EP | disclosed |
| EP-1362045-B1 | 2-THIO-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THE USE THEREOF IN THE PHARMACEUTICAL INDUSTRY | MERCKLE GMBH (DE) | 2004-11-17 | — | — | EP | disclosed |
| US-20040116416-A1 | 2-thio-substituted imidazole derivatives and the use thereof in the pharmaceutical industry | MERCKLE GMBH (DE) | 2004-06-17 | — | — | US | disclosed |
| WO-2003097633-A1 | 2-THIO-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR USE IN PHARMACEUTICS | MERCKLE GMBH (DE) | 2003-11-27 | — | — | WO | disclosed |
| EP-1362045-A2 | 2-THIO-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THE USE THEREOF IN THE PHARMACEUTICAL INDUSTRY | MERCKLE GMBH (DE) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002066458-A2 | 2-THIO-SUBSTITUTED IMIDAZOLE DERIVATIVES AND THE USE THEREOF IN THE PHARMACEUTICAL INDUSTRY | MERCKLE GMBH (DE) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252810-A1 | 2-Thio-substituted imidazole derivatives and their use in pharmaceutics | IL2, TPMT, IFNG | RECQL 1324/4885MAPK1 2717/4885TSHR 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.