Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200876 | 0.81 | KMT2A (0.39) | APLNRNR1H2KMT2ACTSKCTSS | |
| SCHEMBL7926354 | 0.80 | KMT2A (0.38) | APLNRNR1H2KMT2ACTSKCTSS | |
| SCHEMBL21946033 | 0.80 | KMT2A (0.38) | APLNRNR1H2KMT2ACTSKCTSS | |
| SCHEMBL19931893 | 0.79 | KMT2A (0.36) | NR1H2KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL28396159 | 0.78 | KMT2A (0.39) | APLNRNR1H2KMT2ACTSKCTSS | |
| SCHEMBL24106816 | 0.69 | KMT2A (0.35) | KMT2AALDH1A1MEN1MAPK1TDP1 | |
| SCHEMBL22632833 | 0.69 | KMT2A (0.38) | APLNRKMT2ACTSKCTSSMEN1 | |
| SCHEMBL28251999 | 0.69 | KMT2A (0.40) | APLNRNR1H2KMT2ACTSKCTSS | |
| SCHEMBL12173239 | 0.68 | KMT2A (0.38) | APLNRKMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL15306516 | 0.68 | KMT2A (0.38) | APLNRKMT2AALDH1A1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572601-A1 | SOLID-PHASE PREPARATION OF 18 F-LABELLED AMINO ACIDS | GE Healthcare Limited (GB) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056725-A1 | SOLID-PHASE PREPARATION OF 18F-LABELLED AMINO ACIDS | GE HEALTHCARE LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |