Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7926354 | 0.92 | KMT2A (0.38) | KMT2AMEN1MAPK1NR1H2TDP1 | |
| SCHEMBL21946033 | 0.92 | KMT2A (0.38) | KMT2AMEN1MAPK1NR1H2TDP1 | |
| SCHEMBL19931893 | 0.88 | KMT2A (0.36) | KMT2AMEN1MAPK1NR1H2TDP1 | |
| SCHEMBL28396159 | 0.88 | KMT2A (0.39) | KMT2AMEN1MAPK1NR1H2TDP1 | |
| SCHEMBL1980398 | 0.83 | MEN1 (0.43) | KMT2AMEN1MAPK1CACNA1HHDAC4 | |
| SCHEMBL6254239 | 0.81 | APLNR (0.33) | KMT2AMEN1MAPK1NR1H2TDP1 | |
| SCHEMBL4966238 | 0.79 | MEN1 (0.40) | KMT2AMEN1MAPK1CACNA1HHDAC4 | |
| SCHEMBL1088267 | 0.79 | MEN1 (0.40) | KMT2AMEN1MAPK1CACNA1HHDAC4 | |
| SCHEMBL1088268 | 0.79 | MEN1 (0.40) | KMT2AMEN1MAPK1CACNA1HHDAC4 | |
| SCHEMBL1088079 | 0.79 | MEN1 (0.40) | KMT2AMEN1MAPK1CACNA1HHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7264792-B2 | Solid phase preparation of 18F-labelled amino acids | GE HEALTHCARE LIMITED (GB) | 2007-09-04 | — | — | US | disclosed |
| EP-1572601-B1 | SOLID-PHASE PREPARATION OF 18 F-LABELLED AMINO ACIDS | GE HEALTHCARE LTD (GB) | 2007-08-15 | — | — | EP | disclosed |
| US-20060039855-A1 | Solid phase preparation of 18f-labelled amino acids | GE HEALTHCARE LIMITED (GB) | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060039855-A1 | Solid phase preparation of 18f-labelled amino acids | SLC7A5, SLC43A1, SLCO2B1 | KMT2A 1280/4885MEN1 1141/4885MAPK1 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.