Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 18/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623747 | 0.99 | GCK (0.48) | GCKALDH1A1LMNAUSP2MAPK1 | |
| SCHEMBL624715 | 0.88 | GCK (0.57) | GCK | |
| SCHEMBL627287 | 0.88 | GCK (0.51) | GCKALDH1A1LMNAUSP2MAPK1 | |
| SCHEMBL626912 | 0.87 | GCK (0.52) | GCKALDH1A1LMNAUSP2MAPK1 | |
| SCHEMBL625184 | 0.77 | GCK (0.49) | GCK | |
| SCHEMBL625466 | 0.76 | GCK (0.49) | GCK | |
| SCHEMBL626483 | 0.75 | GCK (0.65) | GCKALDH1A1LMNAUSP2MAPK1 | |
| SCHEMBL625064 | 0.74 | GCK (0.57) | GCK | |
| SCHEMBL623375 | 0.73 | GCK (0.57) | GCK | |
| SCHEMBL625071 | 0.71 | GCK (0.48) | GCKALDH1A1LMNAUSP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |