Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624715 | 0.79 | GCK (0.57) | GCK | |
| SCHEMBL185089 | 0.77 | GCK (0.65) | GCKLMNARXFP1KMT2ATP53 | |
| SCHEMBL626672 | 0.72 | GCK (0.62) | GCKLMNAKMT2AALDH1A1USP2 | |
| SCHEMBL625438 | 0.71 | GCK (0.47) | GCKLMNAALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL623747 | 0.70 | GCK (0.48) | GCKLMNAALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL623767 | 0.70 | GCK (0.64) | GCK | |
| SCHEMBL626401 | 0.68 | GCK (0.56) | GCKLMNAKMT2AALDH1A1USP2 | |
| SCHEMBL627263 | 0.68 | GCK (0.51) | GCK | |
| SCHEMBL628093 | 0.67 | ALDH1A1 (0.59) | GCKLMNARXFP1KMT2AALDH1A1 | |
| SCHEMBL623635 | 0.67 | GCK (0.60) | GCKLMNAKMT2AALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |