SCHEMBL6254451

SCHEMBL6254451

O=S(=O)(CBr)Oc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.61
CA2 P00918 5/20 0.52
CA9 Q16790 5/20 0.52
CA1 P00915 4/20 0.52
HTT P42858 1/20 0.43
LMNA P02545 1/20 0.42
PPARG P37231 1/20 0.42
NFE2L2 Q16236 1/20 0.42
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 1/20 0.38
KDM4E B2RXH2 1/20 0.38
SOS1 Q07889 1/20 0.36
STS P08842 1/20 0.36
LTA4H P09960 1/20 0.36
TSHR P16473 1/20 0.36
KCNA3 P22001 1/20 0.36
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11096552 0.83 KMT2A (0.57) KMT2ACA2CA9CA1HTT
SCHEMBL779566 0.81 KMT2A (0.72) KMT2ACA2CA9CA1HTT
SCHEMBL10039237 0.81 KMT2A (0.65) KMT2ACA2CA9CA1HTT
SCHEMBL28423404 0.81 KMT2A (0.55) KMT2ACA2CA9CA1HTT
SCHEMBL775874 0.79 KMT2A (0.63) KMT2ACA2CA9CA1HTT
SCHEMBL29365117 0.79 KMT2A (0.69) KMT2ACA2CA9CA1HTT
SCHEMBL29453015 0.79 KMT2A (0.69) KMT2ACA2CA9CA1HTT
SCHEMBL9146628 0.78 KMT2A (0.57) KMT2ACA2CA9CA1HTT
SCHEMBL6252538 0.77 KMT2A (0.61) KMT2ACA2CA9CA1HTT
SCHEMBL12014821 0.77 KMT2A (0.61) KMT2ACA2CA9CA1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6086764-A Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use CROSSWINDS, INC. (US) 2000-07-11 US claimed
EP-0884096-A1 Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use Crosswinds, Inc. (US) 1998-12-16 EP claimed
CN-103354912-B Patterned retarders 克里斯奥普提克斯株式会社 2016-09-07 CN disclosed
CN-105008378-A Reaction catalyst for cross coupling and method for manufacturing aromatic compound HOKKO CHEM IND CO 2015-10-28 CN disclosed
CN-103765258-A Three-dimensional circular polarization eyeglasses CRYSOPTIX KK 2014-04-30 CN disclosed
CN-103354912-A Patterned retarder CRYSOPTIX KK 2013-10-16 CN disclosed
CN-103238088-A Retarder and liquid crystal display including the same CRYSOPTIX KK 2013-08-07 CN disclosed
CN-102763009-A Polarizer and liquid crystal display including the same CRYSOPTIX KK 2012-10-31 CN disclosed
EP-0884096-B1 Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use KOCH MEMBRANE SYSTEMS INC (US) 2005-09-14 EP disclosed
US-6086764-A Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use CROSSWINDS, INC. (US) 2000-07-11 US disclosed
EP-0884096-A1 Semipermeable encapsulated membranes with improved acid and base stability process for their manufacture and their use Crosswinds, Inc. (US) 1998-12-16 EP disclosed