Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.50 |
| ▸ | CTSS | P25774 | 16/20 | 0.42 |
| ▸ | CTSL | P07711 | 16/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4037568 | 0.93 | CTSK (0.58) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL4042123 | 0.90 | CTSK (0.48) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL4041948 | 0.87 | CTSK (0.67) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL4041741 | 0.85 | CTSK (0.56) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL4044810 | 0.85 | CTSK (0.53) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL4043599 | 0.84 | CTSK (0.55) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL4045326 | 0.84 | CTSK (0.55) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL4045073 | 0.84 | CTSK (0.56) | CTSKCTSSCTSLCTSB | |
| SCHEMBL4040417 | 0.84 | CTSK (0.54) | CTSKCTSSCTSLCTSBCTSV | |
| SCHEMBL4043276 | 0.83 | CTSK (0.56) | CTSKCTSSCTSLCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |