SCHEMBL6254596

SCHEMBL6254596

Oc1cccc(CNCCNCc2cccc(O)c2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A4 P14672 1/20 0.65
CYP1A2 P05177 1/20 0.64
CYP3A4 P08684 1/20 0.64
PKM P14618 1/20 0.64
ALOX15 P16050 1/20 0.64
NFKB1 P19838 1/20 0.64
MAPK1 P28482 1/20 0.64
KMT2A Q03164 2/20 0.62
KDM4E B2RXH2 1/20 0.62
LMNA P02545 1/20 0.62
MAPT P10636 1/20 0.62
BLM P54132 1/20 0.62
PMP22 Q01453 1/20 0.62
DRD2 P14416 2/20 0.56
DRD4 P21917 1/20 0.56
ADRA1D P25100 1/20 0.56
ADRA1A P35348 1/20 0.56
ADRA1B P35368 1/20 0.56
DRD3 P35462 1/20 0.56
MEN1 O00255 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9416529 0.91 SLC2A4 (0.75) SLC2A4CYP1A2CYP3A4PKMALOX15
SCHEMBL2670053 0.90 SLC2A4 (0.59) SLC2A4CYP1A2CYP3A4PKMALOX15
SCHEMBL8584527 0.88 SLC2A4 (0.57) SLC2A4CYP1A2CYP3A4PKMALOX15
SCHEMBL17285992 0.85 CYP1A2 (0.58) SLC2A4CYP1A2CYP3A4PKMALOX15
SCHEMBL17282162 0.84 SLC2A4 (0.53) SLC2A4CYP1A2CYP3A4PKMALOX15
SCHEMBL3197343 0.84 SLC2A4 (0.53) SLC2A4CYP1A2CYP3A4PKMALOX15
SCHEMBL9416667 0.83 SLC2A4 (0.71) SLC2A4CYP1A2CYP3A4PKMALOX15
SCHEMBL1041003 0.83 SLC2A4 (0.61) SLC2A4CYP1A2CYP3A4PKMALOX15
SCHEMBL9328648 0.83 GAA (0.63) SLC2A4KMT2AKDM4EMAPTDRD2
SCHEMBL30967718 0.82 SLC2A4 (0.64) SLC2A4CYP1A2CYP3A4PKMALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1282394-B1 USE OF N,N'-DIBENZYL ETHYLENE DIAMINE N,N'-DIACETIC ACID DERIVATIVES AS ANTI-POLLUTION AGENT OREAL (FR) 2004-09-29 EP claimed
EP-1282394-A1 USE OF N,N'-DIBENZYL ETHYLENE DIAMINE N,N'-DIACETIC ACID DERIVATIVES AS ANTI-POLLUTION AGENT L'OREAL (FR) 2003-02-12 EP claimed
WO-2001087253-A1 USE OF N,N'-DIBENZYL ETHYLENE DIAMINE N,N'-DIACETIC ACID DERIVATIVES AS ANTI-POLLUTION AGENT L'OREAL (FR) 2001-11-22 WO claimed
EP-0820763-A2 Use of N,N'-dibenzyl-ethylene diamine acid derivatives as depigmentation agents L'OREAL (FR) 1998-01-28 EP claimed
EP-1282397-B1 USE OF COMPOUNDS CONTAINING A THIO-ETHER, SULPHOXIDE OR SULPHONE FUNCTION AS COSMETIC ANTI-POLLUTION AGENT OREAL (FR) 2005-05-04 EP disclosed
EP-1282395-B1 USE OF ELLAGIC ACID AS ANTI-POLLUTION COSMETIC AGENT OREAL (FR) 2004-10-06 EP disclosed
EP-1282394-B1 USE OF N,N'-DIBENZYL ETHYLENE DIAMINE N,N'-DIACETIC ACID DERIVATIVES AS ANTI-POLLUTION AGENT OREAL (FR) 2004-09-29 EP disclosed
EP-1282394-A1 USE OF N,N'-DIBENZYL ETHYLENE DIAMINE N,N'-DIACETIC ACID DERIVATIVES AS ANTI-POLLUTION AGENT L'OREAL (FR) 2003-02-12 EP disclosed
WO-2001087253-A1 USE OF N,N'-DIBENZYL ETHYLENE DIAMINE N,N'-DIACETIC ACID DERIVATIVES AS ANTI-POLLUTION AGENT L'OREAL (FR) 2001-11-22 WO disclosed
EP-0820763-B1 Use of N,N'-dibenzyl-ethylene diamine acid derivatives as depigmentation agents OREAL (FR) 2000-09-13 EP disclosed
US-6005006-A BLEACHING AND DEPIGMENTING COMPOUNDS FOR SKIN L'OREAL (FR) 1999-12-21 US disclosed
US-5834518-A FOR APPLICATION TO SKIN L'OREAL (FR) 1998-11-10 US disclosed
EP-0820763-A2 Use of N,N'-dibenzyl-ethylene diamine acid derivatives as depigmentation agents L'OREAL (FR) 1998-01-28 EP disclosed