SCHEMBL6254895

SCHEMBL6254895

CC[Si](CC)(CC)CNC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
FFAR3 O14843 1/20 0.32
EGLN1 Q9GZT9 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
MCL1 Q07820 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11133870 0.72
SCHEMBL15823494 0.69 GAA (0.37) CYP2D6CYP2C19ALDH1A1SMN1; SMN2EGLN1
SCHEMBL10011 0.67
SCHEMBL16610541 0.67 CYP2D6 (0.37) CYP2D6CYP2C19ALDH1A1EGLN1
Water SCHEMBL28848094 0.65 MCL1 (0.46) CYP2D6CYP2C19ALDH1A1SMN1; SMN2FFAR3
Phosphine SCHEMBL28376179 0.65
Bromide SCHEMBL1729291 0.65
Hydrochloric Acid SCHEMBL29551256 0.65 CYP2D6 (0.46) CYP2D6CYP2C19ALDH1A1SMN1; SMN2FFAR3
Ammonia Solution, Strong SCHEMBL28112145 0.65
Propane SCHEMBL28986125 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005063018-A1 HALOALKENE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2005-07-14 WO disclosed
WO-2004052872-A1 HALOALKENE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2004-06-24 WO disclosed