SCHEMBL16610541

SCHEMBL16610541

CO[Si](CNC(=O)O)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
EGLN1 Q9GZT9 2/20 0.33
TSHR P16473 2/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13317345 0.80 KDM4E (0.39) TSHRALDH1A1
SCHEMBL141335 0.80 EPHX1 (0.40) TSHRALDH1A1
SCHEMBL14027917 0.78 TSHR (0.31) TSHR
SCHEMBL20954114 0.78 CYP2D6 (0.36) CYP2D6CYP2C19EGLN1TSHR
SCHEMBL2900184 0.78 TSHR (0.36) CYP2D6CYP2C19EGLN1TSHR
SCHEMBL142089 0.78 CYP2D6 (0.36) CYP2D6CYP2C19EGLN1TSHR
SCHEMBL728026 0.78 TSHR (0.36) TSHR
SCHEMBL3691270 0.78 KMT2A (0.40) CYP2C19EGLN1TSHRALDH1A1
SCHEMBL17132448 0.76 CYP2D6 (0.34) CYP2D6CYP2C19EGLN1
SCHEMBL19753750 0.76 GFPT1 (0.38) CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260071079-A1 USE OF ALKOXY-FUNCTIONAL ORGANIC POLYMERS TO ENHANCE WATER RESISTANCE OF INTUMESCENT COATINGS HILTI AKTIENGESELLSCHAFT (LI) 2026-03-12 US disclosed
EP-3548548-B1 FOAMABLE, MULTI-COMPONENT COMPOSITION WHICH FORMS AN INSULATING LAYER WITH IMPROVED STORAGE STABILITY AND USE OF SAID COMPOSITION HILTI AG (LI) 2025-09-10 EP disclosed
EP-4584341-A1 INTUMESCENT COMPOSITION AND USE OF THE INTUMESCENT COMPOSITION TO INCREASE CHAR STABILITY OF COATINGS IN THE EVENT OF FIRE Hilti Aktiengesellschaft (LI) 2025-07-16 EP disclosed
EP-4584340-A1 USE OF ALKOXY-FUNCTIONAL ORGANIC POLYMERS TO ENHANCE WATER RESISTANCE OF INTUMESCENT COATINGS Hilti Aktiengesellschaft (LI) 2025-07-16 EP disclosed
EP-4225849-B1 FIRE-PROTECTION COATING COMPOSITION AND USE THEREOF HILTI AG (LI) 2024-09-11 EP disclosed
WO-2024052104-A1 USE OF ALKOXY-FUNCTIONAL ORGANIC POLYMERS TO ENHANCE WATER RESISTANCE OF INTUMESCENT COATINGS HILTI AKTIENGESELLSCHAFT (LI) 2024-03-14 WO disclosed
WO-2024052105-A1 INTUMESCENT COMPOSITION AND USE OF THE INTUMESCENT COMPOSITION TO INCREASE CHAR STABILITY OF COATINGS IN THE EVENT OF FIRE HILTI AKTIENGESELLSCHAFT (LI) 2024-03-14 WO disclosed
EP-4335907-A1 USE OF ALKOXY-FUNCTIONAL ORGANIC POLYMERS TO ENHANCE WATER RESISTANCE OF INTUMESCENT COATINGS Hilti Aktiengesellschaft (LI) 2024-03-13 EP disclosed
EP-4335908-A1 INTUMESCENT COMPOSITION AND USE OF THE INTUMESCENT COMPOSITION TO INCREASE CHAR STABILITY OF COATINGS IN THE EVENT OF FIRE Hilti Aktiengesellschaft (LI) 2024-03-13 EP disclosed
US-20230407110-A1 FIRE-PROTECTION COATING COMPOSITION AND USE THEREOF HILTI AKTIENGESELLSCHAFT (LI) 2023-12-21 US disclosed
CN-102971352-A Silane-crosslinked compositions WACKER CHEMIE AG 2013-03-13 CN disclosed
CN-102869734-A Coating composition for sealing surfaces WACKER CHEMIE AG 2013-01-09 CN disclosed
CN-102471595-A Crosslinkable silicone-based compositions WACKER CHEMIE AG 2012-05-23 CN disclosed
CN-102272233-A Polymer blends comprising alkoxysilane-terminated polymers 2011-12-07 CN disclosed
CN-101305028-B Silane-crosslinking adhesive, sealant or coating with a silicic acid filler and use thereof HENKEL AG & CO KGAA 2011-06-29 CN disclosed
CN-101374888-B Polymer mixtures containing alkoxysilane terminated polymers WACKER CHEMIE AG 2011-04-20 CN disclosed
CN-101443417-A Transparent polymer mixtures comprising alkoxysilane-terminated polymers WACKER CHEMIE AG (DE) 2009-05-27 CN disclosed
CN-101443381-A Alkoxysilane-crosslinked polymers with improved resilience properties WACKER CHEMIE AG (DE) 2009-05-27 CN disclosed
CN-101374888-A Polymer mixtures containing alkoxysilane terminated polymers WACKER CHEMIE AG (DE) 2009-02-25 CN disclosed
CN-101305028-A Silane-crosslinking adhesive, sealant or coating with a silicic acid filler and use thereof HENKEL AG & CO KGAA (DE) 2008-11-12 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071079-A1 USE OF ALKOXY-FUNCTIONAL ORGANIC POLYMERS TO ENHANCE WATER RESISTANCE OF INTUMESCENT COATINGS ITGB1, SMC1A, EPCAM CYP2D6 3706/4885CYP2C19 3753/4885EGLN1 1573/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.