SCHEMBL6254896

SCHEMBL6254896

[C]1CNC2CC=CC=C2N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34460307 0.69
SCHEMBL34460214 0.69
Hydrochloric Acid SCHEMBL7545038 0.69
Fluoride SCHEMBL28181689 0.68
SCHEMBL10757720 0.65
SCHEMBL997613 0.65 HDAC8 (0.30)
SCHEMBL28246896 0.62
SCHEMBL7097629 0.62
SCHEMBL19053856 0.61
SCHEMBL29154227 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365511-A1 Antiviral Pyrazolopiridinone Compounds NOVARTIS AG (CH) 2023-11-16 US disclosed
WO-2023154905-A1 ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS GILEAD SCIENCES, INC. (US) 2023-08-17 WO disclosed
US-11667613-B2 Antiviral pyrazolopyridinone compounds NOVARTIS AG (CH) 2023-06-06 US disclosed
CN-114667285-A Antiviral pyrazolopyridinone compounds 诺华股份有限公司 2022-06-24 CN disclosed
US-20210130302-A1 Antiviral Pyrazolopyridinone Compounds NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC 2021-05-06 US disclosed
WO-2021061898-A1 ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS NOVARTIS AG (CH) 2021-04-01 WO disclosed
WO-2005063018-A1 HALOALKENE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2005-07-14 WO disclosed
WO-2004052872-A1 HALOALKENE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2004-06-24 WO disclosed
US-5280034-A Bis-heterocyclic prostaglandin analogs E. R. SQUIBB & SONS, INC. (US) 1994-01-18 US disclosed