SCHEMBL6255121

SCHEMBL6255121

CCCc1c(CCC)c(CCC)c2c(c1CCC)Oc1cccc(Cl)c1O2

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.55
CFTR P13569 2/20 0.34
ALDH1A1 P00352 1/20 0.33
F2RL1 P55085 2/20 0.33
CYP1A1 P04798 2/20 0.33
TAAR1 Q96RJ0 1/20 0.32
DHFR P00374 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5588306 0.89 AHR (0.50) AHRCFTRALDH1A1F2RL1CYP1A1
SCHEMBL5587386 0.80 AHR (0.47) AHRCFTRALDH1A1CYP1A1
SCHEMBL6252702 0.80 ALDH1A1 (0.39) AHRALDH1A1CYP1A1
SCHEMBL5588673 0.79 AHR (0.53) AHRCFTRAKR1B1
Ethane SCHEMBL28414050 0.78 AHR (0.78) AHRALDH1A1
SCHEMBL9579668 0.78
SCHEMBL6256853 0.75 AHR (0.57) AHRALDH1A1CYP1A1
SCHEMBL6254624 0.73 AHR (0.64) AHRALDH1A1
SCHEMBL2438856 0.73 AHR (0.41) AHRALDH1A1F2RL1
SCHEMBL3172291 0.72 AHR (0.69) AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed