Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 12/20 | 0.52 |
| ▸ | PIM1 | P11309 | 6/20 | 0.49 |
| ▸ | FYN | P06241 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625573 | 0.80 | DYRK1A (0.54) | DYRK1APIM1FYN | |
| SCHEMBL28944695 | 0.80 | DYRK1A (0.54) | DYRK1APIM1FYN | |
| SCHEMBL624076 | 0.78 | DYRK1A (0.53) | DYRK1APIM1FYN | |
| SCHEMBL624844 | 0.77 | PIM1 (0.52) | DYRK1APIM1FYN | |
| SCHEMBL625515 | 0.77 | F2RL3 (0.50) | DYRK1A | |
| SCHEMBL3542403 | 0.76 | DYRK1A (0.56) | DYRK1APIM1FYN | |
| SCHEMBL1945252 | 0.76 | DYRK1A (0.52) | DYRK1APIM1FYN | |
| SCHEMBL1946610 | 0.75 | FYN (0.64) | DYRK1APIM1FYN | |
| SCHEMBL1944083 | 0.74 | PIM1 (0.57) | DYRK1APIM1FYN | |
| SCHEMBL1945068 | 0.74 | DYRK1A (0.55) | DYRK1APIM1FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |