Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 15/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625574 | 0.81 | F2RL3 (0.65) | F2RL3 | |
| SCHEMBL624077 | 0.79 | F2RL3 (0.50) | F2RL3MAPTTP53GAADYRK1A | |
| SCHEMBL624845 | 0.78 | F2RL3 (0.52) | F2RL3MAPTTP53GAADYRK1A | |
| SCHEMBL625514 | 0.77 | DYRK1A (0.52) | DYRK1A | |
| SCHEMBL2983371 | 0.77 | MEN1 (0.64) | F2RL3MAPTDYRK1AIRAK4 | |
| SCHEMBL14397224 | 0.76 | F2RL3 (0.47) | F2RL3MAPTTP53GAADYRK1A | |
| SCHEMBL1946612 | 0.76 | F2RL3 (0.49) | F2RL3MAPTTP53GAA | |
| SCHEMBL1944086 | 0.75 | F2RL3 (0.51) | F2RL3MAPTTP53GAADYRK1A | |
| SCHEMBL1945626 | 0.73 | F2RL3 (0.47) | F2RL3MAPTTP53DYRK1ANPC1 | |
| SCHEMBL1945253 | 0.73 | PIM1 (0.47) | F2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020217-A1 | AMINO- IMIDAZOLOTHIADIAZOLES FOR USE AS PROTEIN OR LIPID KINASE INHIBITORS | CENTRO NACIONAL DE INVESTIGACIONES ONCOLÓGICAS (CNIO) (ES) | 2012-02-16 | — | — | WO | disclosed |