SCHEMBL6255191

SCHEMBL6255191

C=C(C)C(=O)O[SiH2]CCCC

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.48
ALDH1A1 P00352 4/20 0.43
THRB P10828 2/20 0.37
CES1 P23141 2/20 0.31
THRA P10827 1/20 0.31
CES2 O00748 3/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618502 0.94 TSHR (0.52) TSHRALDH1A1THRBCES1THRA
SCHEMBL252652 0.88 ALDH1A1 (0.46) TSHRALDH1A1THRB
SCHEMBL21462885 0.86 TSHR (0.49) TSHRALDH1A1THRBTHRACES2
SCHEMBL28365095 0.81 TSHR (0.55) TSHRALDH1A1THRB
SCHEMBL702887 0.79
SCHEMBL1408644 0.77
SCHEMBL19125928 0.77 TSHR (0.59) TSHRALDH1A1THRBTHRACES2
SCHEMBL2184914 0.76 ALDH1A1 (0.35) TSHRALDH1A1
Water SCHEMBL28097391 0.74 TSHR (0.36) TSHRALDH1A1CES1CES2
SCHEMBL5838126 0.74 TSHR (0.36) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3208295-B1 METHOD FOR PRODUCING SILOXANE RESIN KANEKA CORP (JP) 2021-01-13 EP disclosed
US-10040907-B2 Method for producing siloxane resin KANEKA CORPORATION (JP) 2018-08-07 US disclosed
EP-3208295-A1 METHOD FOR PRODUCING SILOXANE RESIN Kaneka Corporation (JP) 2017-08-23 EP disclosed
US-20170204226-A1 METHOD FOR PRODUCING SILOXANE RESIN KANEKA CORPORATION (JP) 2017-07-20 US disclosed
EP-1572702-A1 PROCESS FOR THE PRODUCTION OF SILYL CARBOXYLATE MONOMERS SIGMA COATINGS B.V. (NL) 2005-09-14 EP disclosed
WO-2004056838-A1 PROCESS FOR THE PRODUCTION OF SILYL CARBOXYLATE MONOMERS SIGMA COATINGS B.V. (NL) 2004-07-08 WO disclosed
EP-1295888-A1 Process for the preparation of trialkylsilylated carboxylate monomers, the obtained trialkylsilylated carboxylate monomers and their use in antifouling coatings SIGMA COATINGS B.V. (NL) 2003-03-26 EP disclosed