Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | RAB9A | P51151 | 4/20 | 0.76 |
| ▸ | NPC1 | O15118 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.76 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.76 |
| ▸ | XBP1 | P17861 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.62 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 11/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624500 | 0.96 | HTT (0.70) | HTTMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28253631 | 0.86 | MAPT (1.00) | HTTMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20609252 | 0.86 | MAPT (1.00) | HTTMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29019998 | 0.86 | MAPT (0.57) | HTTMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29019996 | 0.86 | MAPT (0.57) | HTTMAPTRAB9ANPC1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7253425 | 0.83 | HTT (0.54) | HTTMAPTRAB9ANPC1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL6997178 | 0.83 | HTT (0.54) | HTTMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL812295 | 0.80 | ALDH1A1 (1.00) | HTTMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1524525 | 0.80 | ALDH1A1 (1.00) | HTTMAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL809531 | 0.80 | ALDH1A1 (1.00) | HTTMAPTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021692-A1 | CURCUMIN ANALOGS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-02-16 | — | — | WO | disclosed |