Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 10/20 | 0.56 |
| ▸ | DRD2 | P14416 | 9/20 | 0.56 |
| ▸ | DRD3 | P35462 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CPT2 | P23786 | 1/20 | 0.49 |
| ▸ | CPT1A | P50416 | 1/20 | 0.49 |
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468773 | 0.88 | DRD4 (0.61) | DRD4DRD2DRD3HTTCPT2 | |
| SCHEMBL3323023 | 0.80 | DRD4 (0.53) | DRD4DRD2DRD3HTTCPT2 | |
| SCHEMBL6270506 | 0.80 | DRD4 (0.60) | DRD4DRD2DRD3HTTCPT2 | |
| SCHEMBL1653301 | 0.79 | HTT (0.79) | DRD4DRD2DRD3HTTCPT2 | |
| SCHEMBL27812289 | 0.76 | HTT (0.56) | DRD4DRD2DRD3HTTCPT2 | |
| SCHEMBL2374222 | 0.74 | DRD4 (0.67) | DRD4DRD2DRD3USP30 | |
| SCHEMBL3323017 | 0.74 | HTT (0.52) | DRD4DRD2DRD3HTTCPT2 | |
| SCHEMBL10070514 | 0.74 | HTT (0.56) | DRD4DRD2DRD3HTTCPT2 | |
| SCHEMBL1653117 | 0.73 | DRD2 (0.56) | DRD4DRD2DRD3HTTCPT2 | |
| SCHEMBL2838187 | 0.73 | USP30 (0.51) | DRD4DRD2DRD3HTTCPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061485-A1 | PROCESS FOR MAKING SUBSTITUTED PYRAZOLES | PHARMACIA CORPORATION (US) | 2005-07-07 | — | — | WO | claimed |
| WO-2005061485-A1 | PROCESS FOR MAKING SUBSTITUTED PYRAZOLES | PHARMACIA CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |