Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5361000 | 0.90 | HSD17B2 (0.54) | AOC3HSD17B1HSD17B2HCAR2CTSV | |
| SCHEMBL5360998 | 0.80 | HCAR2 (0.43) | HCAR2CTSVCTSLPPARGTOP2A | |
| SCHEMBL6255537 | 0.79 | CTSV (0.43) | ALDH1A1MAPTHCAR2CTSVCTSL | |
| SCHEMBL6255535 | 0.78 | HCAR2 (0.44) | HCAR2CTSVCTSLPPARGTOP2A | |
| SCHEMBL5359847 | 0.75 | HSD17B2 (0.59) | AOC3HSD17B1HSD17B2ALDH1A1SIRT2 | |
| SCHEMBL5360569 | 0.74 | SIRT2 (0.44) | AOC3HSD17B1HSD17B2CTSVCTSL | |
| SCHEMBL5363528 | 0.73 | POLB (0.54) | AOC3HSD17B1HSD17B2HPGDSIRT2 | |
| SCHEMBL6475966 | 0.73 | MEN1 (0.54) | ALDH1A1MAPTHPGDSIRT2 | |
| SCHEMBL5356017 | 0.71 | KMT2A (0.52) | AOC3HCAR2 | |
| SCHEMBL5355948 | 0.71 | AOC3 (0.49) | AOC3SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572629-A1 | COMPOUNDS WHICH MODULATE PPARϝ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004052840-A1 | COMPOUNDS WHICH MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-24 | — | — | WO | disclosed |