⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255674 | 1.00 | — | — | |
| SCHEMBL6898983 | 0.93 | — | — | |
| SCHEMBL6258448 | 0.86 | — | — | |
| SCHEMBL6258446 | 0.86 | — | — | |
| SCHEMBL28685175 | 0.81 | — | — | |
| SCHEMBL6258539 | 0.74 | MEN1 (0.38) | — | |
| SCHEMBL18023048 | 0.74 | — | — | |
| SCHEMBL6130157 | 0.71 | ALDH1A1 (0.38) | — | |
| SCHEMBL6259562 | 0.70 | TSHR (0.37) | — | |
| SCHEMBL18023111 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114106262-B | Polycarboxylic slump retaining agent and preparation method thereof | 北京市建筑工程研究院有限责任公司 | 2022-11-04 | — | — | CN | claimed |
| CN-114230728-A | Polycarboxylate superplasticizer and preparation method thereof | 北京市建筑工程研究院有限责任公司 | 2022-03-25 | — | — | CN | claimed |
| CN-114106262-A | Polycarboxylic slump retaining agent and preparation method thereof | 北京市建筑工程研究院有限责任公司 | 2022-03-01 | — | — | CN | claimed |
| WO-2005068410-A1 | ETHER COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-07-28 | — | — | WO | claimed |
| US-20040192771-A1 | Ether compounds and compositions for cholesterol management and related uses | ESPERION THERAPEUTICS, INC. | 2004-09-30 | — | — | US | claimed |
| US-20030018013-A1 | Ether compounds and compositions for cholesterol management and related uses | ESPERION THERAPEUTICS, INC. | 2003-01-23 | — | — | US | claimed |
| CN-114106262-B | Polycarboxylic slump retaining agent and preparation method thereof | 北京市建筑工程研究院有限责任公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-114230728-A | Polycarboxylate superplasticizer and preparation method thereof | 北京市建筑工程研究院有限责任公司 | 2022-03-25 | — | — | CN | disclosed |
| CN-114106262-A | Polycarboxylic slump retaining agent and preparation method thereof | 北京市建筑工程研究院有限责任公司 | 2022-03-01 | — | — | CN | disclosed |
| WO-2005068410-A1 | ETHER COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-07-28 | — | — | WO | disclosed |
| US-6713507-B2 | CARDIOVASCULAR DISORDERS; ANTILIPEMIC AGENTS; ALZHEIMER'S DISEASE | ESPERION THERAPEUTICS, INC. | 2004-03-30 | — | — | US | disclosed |
| EP-1351916-A2 | ETHER COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | Esperion Therapeutics Inc. (US) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002030863-A2 | ETHER COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2002-04-18 | — | — | WO | disclosed |