Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | CALML3 | P27482 | 1/20 | 0.43 |
| ▸ | SDHA | P31040 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6254889 | 0.91 | F10 (0.45) | F10SLC2A1LMNAPOLBPKM | |
| SCHEMBL6275159 | 0.88 | F10 (0.44) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL7132802 | 0.86 | F10 (0.45) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL6239753 | 0.85 | F10 (0.45) | F10LMNAPOLBPKMKMT2A | |
| SCHEMBL6233472 | 0.84 | MGLL (0.44) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL29085031 | 0.84 | F10 (0.49) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL6236460 | 0.84 | F10 (0.49) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL14448209 | 0.83 | MAOB (0.65) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL6237098 | 0.81 | F10 (0.56) | F10MAOAMAOBLMNAPTGS1 | |
| SCHEMBL6239389 | 0.81 | F10 (0.56) | F10MAOAMAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005003087-A2 | OXAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS | ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2005-01-13 | — | — | WO | claimed |
| WO-2005003087-A2 | OXAZOLE DERIVATIVES AS ANTIBACTERIAL AGENTS | ORCHID CHEMICALS AND PHARMACEUTICALS LTD. (IN) | 2005-01-13 | — | — | WO | disclosed |