Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6252852 | 0.90 | CLK4 (0.41) | ADORA2AADORA1ADORA2BGABRG2GABRB3 | |
| SCHEMBL6252571 | 0.87 | ADORA2A (0.44) | ADORA2AADORA1ADORA2BGABRG2GABRB3 | |
| SCHEMBL6252874 | 0.85 | TSHR (0.39) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL6257635 | 0.84 | CLK4 (0.45) | ADORA2AADORA1ADORA2BGABRG2GABRB3 | |
| SCHEMBL6256103 | 0.79 | MAPT (0.35) | ALDH1A1MAPK1 | |
| SCHEMBL6255956 | 0.78 | RAB9A (0.40) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL6257078 | 0.77 | CLK4 (0.44) | ADORA2AADORA1ADORA2BGABRG2GABRB3 | |
| SCHEMBL6257694 | 0.77 | TAAR1 (0.38) | ADORA2AADORA1ADORA2BALDH1A1CYP3A4 | |
| SCHEMBL6259118 | 0.75 | DYRK1A (0.41) | ADORA2ACLK4ADRA2CALDH1A1CYP1A2 | |
| SCHEMBL6252559 | 0.75 | ESR2 (0.39) | GABRG2GABRB3GABRA5GABRA3CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143538-B1 | Organic electroluminescent element containing a silacyclopentadiene derivative | CHISSO CORP (JP) | 2005-09-14 | — | — | EP | disclosed |
| EP-0754691-B1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORP (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-1143538-A1 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | Chisso Corporation (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6051319-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 2000-04-18 | — | — | US | disclosed |
| US-5986121-A | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1999-11-16 | — | — | US | disclosed |
| EP-0754691-A2 | Silacyclopentadiene derivatives and an organic electroluminescent element obtained by using the silacyclopentadiene derivative | CHISSO CORPORATION (JP) | 1997-01-22 | — | — | EP | disclosed |