Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.68 |
| ▸ | ESR1 | P03372 | 9/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | PGR | P06401 | 4/20 | 0.65 |
| ▸ | AR | P10275 | 4/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.65 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.65 |
| ▸ | SNCA | P37840 | 3/20 | 0.65 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.65 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.63 |
| ▸ | STS | P08842 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5680184 | 1.00 | SHBG (0.68) | SHBGESR1ESR2LMNAPGR | |
| SCHEMBL5681898 | 1.00 | SHBG (0.68) | SHBGESR1ESR2LMNAPGR | |
| SCHEMBL6258554 | 1.00 | SHBG (0.68) | SHBGESR1ESR2LMNAPGR | |
| SCHEMBL5679650 | 1.00 | SHBG (0.68) | SHBGESR1ESR2LMNAPGR | |
| SCHEMBL4593726 | 1.00 | SHBG (0.68) | SHBGESR1ESR2LMNAPGR | |
| SCHEMBL6255675 | 1.00 | SHBG (0.68) | SHBGESR1ESR2LMNAPGR | |
| SCHEMBL14116626 | 1.00 | SHBG (0.68) | SHBGESR1ESR2LMNAPGR | |
| SCHEMBL3357076 | 1.00 | SHBG (0.68) | SHBGESR1ESR2LMNAPGR | |
| SCHEMBL5678022 | 1.00 | SHBG (0.68) | SHBGESR1ESR2LMNAPGR | |
| SCHEMBL5677831 | 1.00 | SHBG (0.68) | SHBGESR1ESR2LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580192-A2 | 16-Hydroxyestratrienes as selective estrogens | Schering AG (DE) | 2005-09-28 | — | — | EP | claimed |
| EP-1580192-A2 | 16-Hydroxyestratrienes as selective estrogens | Schering AG (DE) | 2005-09-28 | — | — | EP | disclosed |